Results 41 to 50 of about 183,332 (357)

Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta–Mediated Epithelial–Mesenchymal Transition

Frontiers in Pharmacology, 2020
Tubulointerstitial renal fibrosis is a chronic disease process affecting chronic kidney disease (CKD). While the etiological role of transforming growth factor-beta (TGF-β) is well known for epithelial–mesenchymal transition (EMT) in chronic kidney ...
Seonghun Kim, Seonghun Kim, Cheol-Hee Jeong, Sang Hyun Song, Jo Eun Um, Hyun Sil Kim, Hyun Sil Kim, Jun Seop Yun, Jun Seop Yun, Dawool Han, Dawool Han, Eunae Sandra Cho, Eunae Sandra Cho, Bo Young Nam, Jong In Yook, Jong In Yook, Minhee Ku, Minhee Ku, Jaemoon Yang, Jaemoon Yang, Man-Deuk Kim, Nam Hee Kim, Tae-Hyun Yoo   +22 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Renal Function during Contralateral Arterial or Ureteral Obstruction

Kidney and Blood Pressure Research, 1978
Excretory function of one kidney of the rat was reduced acutely by either partial renal arterial occlusion, elevation of ureteral pressure or complete ligation of the renal pedicle. U_Na·V by the opposite kidney increased approximately twofold during partial arterial occlusion or elevated ureteral pressure and this was not ...
Ettore Bartoli, Laurence E. Earley, John D. Conger   +2 more
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

The Current Status of Liver Transplantation. [PDF]

, 1971
More than thirty patients have now undergone liver transplantation in Denver, some more than once, and survivals of up to two and a half years have been achieved. Through this and other experience it has been learned that graft viability is more critical
Starzl, Thomas E
core   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Frequency and Predictors of Renal Artery Stenosis in Patients Undergoing Simultaneous Coronary and Renal Catheterization [PDF]

Journal of Tehran University Heart Center, 2012
Background: Atherosclerotic renal artery stenosis (ARAS) remains underdiagnosed due to its nonspecific demonstrations. We aimed to both estimate the frequency of ARAS in high-risk non-selected patients undergoing simultaneous coronary and renal ...
Navid Rokni, Mojtaba Salarifar, Elham Hakki Kazazi, Elham Hakki Kazazi, Hamidreza Goodarzynejad   +4 more
doaj   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Spontaneous renal artery thrombosis: A rare cause of acute flank pain

Radiology Case Reports, 2021
Spontaneous renal artery thrombosis is a rare cause of flank pain and can have fatal consequences. We report a case of acute renal artery thrombosis in a 61-year-old man who experienced flank pain and had no medical history.
Hee Joong Lim, MD, Jung Han Hwang, MD, Jeong Ho Kim, MD, Suyoung Park, MD, Ki Hyun Lee, MD, So Hyun Park, MD   +5 more
doaj  

Acute renal artery thrombosis after kidney transplantation

Jornal Vascular Brasileiro, 2014
Early kidney transplant loss as a result of acute thrombosis of the renal artery remains a constant and devastating complication, with an incidence of 0.2-7.5%.
Murat Özban, Cagatay Aydin, Onur Birsen, Belda Dursun, Halil Erbis, Koray Tekin   +5 more
doaj   +1 more source