Results 161 to 170 of about 67,540 (236)

The anti‐fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 7, Page 1502-1516, April 2026.
Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy   +10 more
wiley   +1 more source

Detection of the Heterozygous Recurrent MAX p.(Arg60Gln) Variant in Two Females Confirms and Expands the Phenotypic Spectrum of Polydactyly–Macrocephaly Syndrome

open access: yesClinical Genetics, Volume 109, Issue 4, Page 788-795, April 2026.
We identified a recurrent heterozygous MAX c.179G>A:p.Arg60Gln variant in two unrelated females affected with the emerging phenotypes of MAX‐associated polydactyly‐macrocephaly syndrome. We propose that genitourinary abnormalities, including Mayer–Rokitanski–Kuster–Hauser syndrome in one individual, are an expansion of the known phenotypes associated ...
Iftekhar A. Showpnil   +9 more
wiley   +1 more source

A Case of Drug-Resistant Renovascular Hypertension due to Renal Artery Stenosis Successfully Treated by Nephrectomy of the Affected Kidney. [PDF]

open access: yesIJU Case Rep
Shimoda M   +9 more
europepmc   +1 more source

CMR‐derived skeletal muscle T1 time and extracellular volume as novel diagnostic markers for cardiac amyloidosis

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
This study compared T1 time and ECV in cardiac and thoracic skeletal muscle using CMR in 267 CA patients and 1709 non‐CA controls. Representative T1‐maps (central panel) illustrate regions of interest placed in the cardiac and thoracic skeletal muscle.
Christina Kronberger   +20 more
wiley   +1 more source

Diagnostic Testing Patterns Influence the Detected Burden of Hypertension‐Mediated Organ Damage in Hospitalized Hypertensive Patients

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Hypertension‐mediated organ damage (HMOD) plays a central role in cardiovascular risk stratification, yet real‐world implementation of guideline‐recommended screening remains heterogeneous across Asian healthcare systems. We conducted a retrospective cross‐sectional study of 315 hospitalized hypertensive patients admitted to a Vietnamese ...
The Dung Bui   +10 more
wiley   +1 more source

Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real‐World Single‐Center Observational Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Patients referred to specialist hypertension clinics often have complex disease characterized by secondary causes, treatment resistance and coexisting kidney disease. Real‐world outcome data in this setting remain limited. We conducted a retrospective cohort study of 199 patients attending a tertiary hypertension clinic between January 2017 ...
William R. Marshall   +5 more
wiley   +1 more source

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