Results 211 to 220 of about 1,001,986 (296)

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Repeat renal biopsy findings in 82 lupus nephritis patients: a clinicopathological study. [PDF]

Int J Clin Exp Pathol
Li S, Yang K, Zhao C, Dong F, Zeng W, Wen J, He Z, Huang W, Qin F.   +8 more
europepmc   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Intravascular large B-cell lymphoma presenting as encephalomyelitis diagnosed by renal biopsy: a case report. [PDF]

BMC Neurol
Ma J, Song D, Yu X, Wang T, Shen Y, Ma L, Wang X.   +6 more
europepmc   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao, Xianhui Liang, Bingyu Li, Bohan Chen, Xiaoyang Wang, Mei Hong, Qi Feng, Yingjin Qiao, Zhangsuo Liu, Kai Wang, Pei Wang   +10 more
wiley   +1 more source

Consensus on core competencies for simulation training in ultrasound-guided renal biopsy. [PDF]

PLoS One
Doyle AJ, Cantwell CP, Mulhall C, Arnett R, Condron CM.   +4 more
europepmc   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Epidemiological study of renal involvement in sarcoidosis in Japan using the Japan Renal Biopsy Registry. [PDF]

Clin Exp Nephrol
Kamata Y, Konta T, Nakano T, Masuzawa N, Ichikawa K, Ozeki T, Maruyama S, Committee for Renal Biopsy, Disease Registry of the Japanese Society of Nephrology.   +8 more
europepmc   +1 more source

Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio, Marjori Lima Boblitz Parente, Ronald Feitosa Pinheiro   +2 more
wiley   +1 more source

A Rare Presentation of Sjögren's Syndrome With Hypokalemic Periodic Paralysis Treated Based on Renal Biopsy Findings. [PDF]

Cureus
Hara M, Ueda M, Hata K, Ueno R.
europepmc   +1 more source