Results 51 to 60 of about 218,306 (297)
Background: An adequate renal biopsy is essential for diagnosis and treatment of medical renal disease. Objective: We evaluated two initiatives to improve adequacy of renal biopsy samples at our centre. Design: Retrospective determination of renal biopsy
Laurette Geldenhuys +7 more
doaj +1 more source
Effect of Proteinuria and Glomerular Filtration Rate on Renal Outcome in Patients with Biopsy-Proven Benign Nephrosclerosis. [PDF]
BACKGROUND:Reduced estimated glomerular filtration rate (eGFR) and proteinuria are risk factors for end-stage renal disease (ESRD), of which benign nephrosclerosis is a common cause.
Keiichi Sumida +15 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A novel method for assessing the renal biopsy specimens using an activatable fluorescent probe [PDF]
Gamma-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is an activatable fluorescent probe that can be activated by γ-glutamyltranspeptidase (GGT). The expression of GGT in the kidney, which is one of the major organs exhibiting enhanced GGT expression,
Fukuda, Satoko +45 more
core +1 more source
Background and aim Chronic kidney disease (CKD) diagnosed when renal damage or diminished glomerular filtration rate persists for over 3 months, indicated by abnormalities like creatinine clearance and proteinuria, aims to compare renal Doppler ...
Ahmed A.A.-R. Ahmed +3 more
doaj +1 more source
Background The use of percutaneous needle biopsy in the evaluation of indeterminate renal masses is controversial and its role in management remains largely unclear. We set to establish current practice on this issue in UK urology departments. Methods We
Arya Manit +5 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Objective This retrospective analysis evaluated the prognostic value of renal response status 2 years after biopsy-proven lupus nephritis (LN) for the prediction of long-term renal outcomes.Methods Eligible patients with SLE as per American College of ...
Qinggong Fu +7 more
doaj +1 more source
To Biopsy a Small Renal Mass, or Not? [PDF]
The abundant use of cross-sectional imaging has markedly increased the diagnosis of small renal masses (SRMs) (1). A strict definition of small renal masses is lacking and most authors consider lesions < 4cm as small (2). According to the literature, 20% of SRMs are benign in formal histological results and SRMs represent 48-66% of diagnosed renal cell
Chatzidarellis, E. +2 more
openaire +3 more sources
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source

