Results 191 to 200 of about 1,269,390 (393)

Pengaruh dopamin, dobutamin dan campuran dopamin-dobutamin terhadap tahanan vaskular dan ginjal =The effect ofDopamine, Dobutamine and Mixed Dopamtne-Dobutamine onHind-limband Renal Vascular Resistance [PDF]

open access: yes, 2001
The aim of this study was to detect the different effects of dopamine, dobutamine with dosages of 2,5 and 10 mgr/KgBW/minute as well as mixed dopamine-dobutamine on hind-limb and renal vascular resistance.
Hadi Sarosa *, R. Sjarif, Bambang Soempeno
core   +1 more source

3‐D Sustained‐Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells

open access: yesAdvanced Science, EarlyView.
Schematic representation of mechanisms by which the 3‐D sustained‐release culture carrier prevents accumulation of ROS by continuously releasing C‐176@PDA‐NPs and inhibiting the cGAS‐STING activated by sudden hypoxia, thereby preventing ferroptosis and promoting differentiation in SSCs and ultimately attenuating IVDD progression.
Liwen Luo   +12 more
wiley   +1 more source

Smoking effects on renal and central hemodynamics in men and women with essential arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2009
Aim. To compare renal and central hemodynamic parameters in smoking and non-smoking men and women with essential arterial hypertension (EAH).Material and methods.
V. I. Podzolkov   +2 more
doaj  

A Mitochondria‐Targeted Biomimetic Nanomedicine Capable of Reversing Drug Resistance in Colorectal Cancer Through Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Chemoresistance and metastasis are the main obstacles to the clinical success of anticancer treatment and are responsible for most cancer deaths in CRC. This study develops a sequentially targeted and mitochondrion‐dysfunctional nanodrug (OXA@Exo‐RD) that simultaneously enhances drug concentration and potency in the targeted organelle to overcome ...
Xiaohui Wang   +9 more
wiley   +1 more source

Features arterial renal blood flow in acute pancreatitis

open access: yesКубанский научный медицинский вестник, 2015
Doppler ultrasound dynamic in interlobar arteries allows indirectly assess arterial blood flow component intraorganic, state microvasculature of kidneys when they are damaged on the background of endotoxemia, as well as state of the peripheral vascular ...
Yu. S. Vinnik   +5 more
doaj  

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou   +7 more
wiley   +1 more source

Thermal oscillations in rat kidneys: an infrared imaging study [PDF]

open access: yes
A high-resolution infrared (IR) camera was used to assess rhythmicity in localized renal blood flow, including the extent of regions containing nephrons with spontaneous oscillations in their individual blood flow.
Elster, Eric   +2 more
core   +2 more sources

HUWE1‐Mediated Degradation of MUTYH Facilitates DNA Damage and Mitochondrial Dysfunction to Promote Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
MutY homolog (MUTYH) protein levels are significantly decreased in the kidneys of acute kidney injury (AKI) patients. The upregulation of the E3 ligase HUWE1 mediates the degradation of MUTYH in renal tubular epithelial cells, exacerbating DNA damage in both the nucleus and mitochondria, thereby promoting AKI. Targeting the HUWE1/MUTYH pathway may be a
Yunwen Yang   +10 more
wiley   +1 more source

Decreasing the blood flow of non-compressible intra-abdominal organs with non-invasive transcutaneous electrical stimulation

open access: yesScientific Reports
Non-invasive neuromodulation of non-compressible internal organs has significant potential for internal organ bleeding and blood-shift in aero/space medicine.
Yusuf O. Cakmak   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy