Results 201 to 210 of about 1,269,390 (393)

Assessing Renal Microvascular Reactivity by Laser Speckle-Contrast Imaging in Angiotensin-II-Treated Mice

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2020
Nicolas Mottard,1,2 Dan E Berkowitz,1,3 Lakshmi Santhanam1,3 1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Department of Anesthesiology and Critical Care, Clinique de la ...
Mottard N, Berkowitz DE, Santhanam L
doaj  

Focus on renal blood flow in mechanically ventilated patients with SARS-CoV-2: a prospective pilot study. [PDF]

open access: yesJ Clin Monit Comput, 2022
Fogagnolo A   +9 more
europepmc   +1 more source

Lactylation‐Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib

open access: yesAdvanced Science, EarlyView.
HECTD2 serves as an E3 ubiquitin ligase of KEAP1 to facilitate the antioxidative response and contributes to lenvatinib resistance in hepatocellular carcinoma. Lactylation of histone 3 on lysine residue 18 drives HECTD2 transcription. Targeting HECTD2 using PLGA‐PEG‐based nanoparticles offers novel strategies to overcome lenvatinib resistance in ...
Runyu Dong   +12 more
wiley   +1 more source

Ex Vivo Simultaneous H215O Positron Emission Tomography and Magnetic Resonance Imaging of Porcine Kidneys—A Feasibility Study

open access: yesJournal of Imaging
The aim was to establish combined H215O PET/MRI during ex vivo normothermic machine perfusion (NMP) of isolated porcine kidneys. We examined whether changes in renal arterial blood flow (RABF) are accompanied by changes of a similar magnitude in renal ...
Maibritt Meldgaard Arildsen   +11 more
doaj   +1 more source

Photoacoustic Imaging in Inflammatory Orthopedic Diseases: Progress toward Precise Diagnostics and Predictive Regulation

open access: yesAdvanced Science, EarlyView.
With the intensification of aging issues, inflammatory orthopedic diseases almost occurs in every elderly people, which are becoming increasingly severe. Persistent inflammation of joints often leads to irreversible tissue damage and loss of organ function, while early diagnosis and timely intervention are crucial for reducing the personal and social ...
Mengyi Huang   +7 more
wiley   +1 more source

Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. [PDF]

open access: yesCardiovasc Res, 2021
Wu J   +13 more
europepmc   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

open access: yesAdvanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang   +5 more
wiley   +1 more source

Assessing Sensitivity of Brain-to-Scalp Blood Flows in Laser Speckle Imaging by Occluding the Superficial Temporal Artery [PDF]

open access: yesarXiv
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due to the scalp and skull, which obstruct direct brain access and contain their own blood dynamics that must be ...
arxiv  

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