Results 201 to 210 of about 1,269,390 (393)
Nicolas Mottard,1,2 Dan E Berkowitz,1,3 Lakshmi Santhanam1,3 1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Department of Anesthesiology and Critical Care, Clinique de la ...
Mottard N, Berkowitz DE, Santhanam L
doaj
Focus on renal blood flow in mechanically ventilated patients with SARS-CoV-2: a prospective pilot study. [PDF]
Fogagnolo A+9 more
europepmc +1 more source
Lactylation‐Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib
HECTD2 serves as an E3 ubiquitin ligase of KEAP1 to facilitate the antioxidative response and contributes to lenvatinib resistance in hepatocellular carcinoma. Lactylation of histone 3 on lysine residue 18 drives HECTD2 transcription. Targeting HECTD2 using PLGA‐PEG‐based nanoparticles offers novel strategies to overcome lenvatinib resistance in ...
Runyu Dong+12 more
wiley +1 more source
The aim was to establish combined H215O PET/MRI during ex vivo normothermic machine perfusion (NMP) of isolated porcine kidneys. We examined whether changes in renal arterial blood flow (RABF) are accompanied by changes of a similar magnitude in renal ...
Maibritt Meldgaard Arildsen+11 more
doaj +1 more source
Renal Blood Flow, Glomerular Filtration Rate, Renal PAH Extraction Ratio, and the Role of the Renal Vasomotor Nerves in the Unanesthetized Rabbit [PDF]
PAUL I. Pascoe, Yvonne Körner
openalex +1 more source
With the intensification of aging issues, inflammatory orthopedic diseases almost occurs in every elderly people, which are becoming increasingly severe. Persistent inflammation of joints often leads to irreversible tissue damage and loss of organ function, while early diagnosis and timely intervention are crucial for reducing the personal and social ...
Mengyi Huang+7 more
wiley +1 more source
Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. [PDF]
Wu J+13 more
europepmc +1 more source
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang+5 more
wiley +1 more source
Assessing Sensitivity of Brain-to-Scalp Blood Flows in Laser Speckle Imaging by Occluding the Superficial Temporal Artery [PDF]
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due to the scalp and skull, which obstruct direct brain access and contain their own blood dynamics that must be ...
arxiv