Results 131 to 140 of about 24,089 (298)

Quality of Life of Patients with Renal Calculi: An Observational Research

open access: yes, 2016
Kidney stones are responsible for about 3.66 million medical consults each year with treatment costing about $2 billion annually in medical bills. The main objective of the study was to analyze the quality of life of patients by existing renal calculi ...
null Samiha Shah Khan   +4 more
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

Urinary Calculi

open access: yes, 1945
When urinary calculi are formed in the uriniferous tubules, they are called renal calculi. When calculi form in the pelvis of the kidney, they are known as pelvic calculi. If the bladder is the site of the production of the concretion it is designated as
Maddy, Keith
core  

RESULTS OF SURGICAL TREATMENT FOR CALCULI IN SOLITARY KIDNEY OR STAGHORN CALCULI IN BILATERAL KIDNEY [PDF]

open access: yes, 1972
Operations for renal calculi performed during a 15-year period in Osaka University Hospital have been reviewed. The patients with staghorn calculi in both kidneys or in the solitary kidney were treated operatively despite poor surgical risks and the ...
竹内, 正文   +6 more
core  

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Renal calculi chemical composition [PDF]

open access: yes, 2016
Department of Urology and Surgical Nephrology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova, The 6th International Medical Congress for Students and Young Doctors, May 12-14, 2016Introduction ...
Seicanu, Cristina
core  

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

RENAL CELL CARCINOMA ASSOCIATED WITH RENAL CALCULI : REPORT OF A CASE [PDF]

open access: yes, 1973
A 50•year-old man was seen with gross hematuria and the urinary retention. X-ray showed gross stone in the right kidney. Nephrectomy was done, and the specimen was that of typical renal cell carcinoma occupying the upper and middle thirds.
重松, 俊朗   +2 more
core  

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

open access: yesAdvanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng   +10 more
wiley   +1 more source

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