Results 301 to 310 of about 1,140,223 (331)
Scandinavian Journal of Surgery, 2004 RENAL CELL CARCINOMA (RCC) accounts for approximately 3% of adult malignancy and 90% to 95% of neoplasms arising from the kidney. It is the sixth leading cause of cancer death in the United States. Approximately 31200 new cases of RCC were diagnosed in the United States in 2000 and more than 11900 affected individuals died.
Mirja Ruutu, Börje Ljungberg
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Current Opinion in Oncology, 2005
This review focuses on recent developments in the biology and clinical therapeutics of renal cell carcinoma. Given historically limited advances in this disease, a more thorough understanding and testing of rationally targeted agents is needed.Von Hippel-Lindau gene inactivation is observed in most clear cell renal carcinoma, driving the malignant ...
Brian I, Rini +2 more
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This review focuses on recent developments in the biology and clinical therapeutics of renal cell carcinoma. Given historically limited advances in this disease, a more thorough understanding and testing of rationally targeted agents is needed.Von Hippel-Lindau gene inactivation is observed in most clear cell renal carcinoma, driving the malignant ...
Brian I, Rini +2 more
openaire +6 more sources
Current Opinion in Oncology, 1993
Renal cell carcinoma remains a challenge for oncologists, with only 20% of patients being cured by surgical removal of the involved kidney and a handful of patients with advanced disease being cured by surgery, immunotherapy, or both. Although advances in early detection, recognition of high-risk groups, and chemotherapy remain disappointing, advances ...
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Renal cell carcinoma remains a challenge for oncologists, with only 20% of patients being cured by surgical removal of the involved kidney and a handful of patients with advanced disease being cured by surgery, immunotherapy, or both. Although advances in early detection, recognition of high-risk groups, and chemotherapy remain disappointing, advances ...
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The Lancet, 2009
Considerable progress has been made in the treatment of patients with renal cell carcinoma, with innovative surgical and systemic strategies revolutionising the management of this disease. In localised disease, partial nephrectomy for small tumours and radical nephrectomy for large tumours continue to be the gold-standard treatments, with emphasis on ...
Bernard Escudier +2 more
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Considerable progress has been made in the treatment of patients with renal cell carcinoma, with innovative surgical and systemic strategies revolutionising the management of this disease. In localised disease, partial nephrectomy for small tumours and radical nephrectomy for large tumours continue to be the gold-standard treatments, with emphasis on ...
Bernard Escudier +2 more
openaire +5 more sources
Hospital Practice, 1987
A doubling in tumor size increases metastases 10-fold and reduces surgical curability drastically. Early diagnosis, abetted by CT and ultrasound scanning, is critical.
John H. Lynch +2 more
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A doubling in tumor size increases metastases 10-fold and reduces surgical curability drastically. Early diagnosis, abetted by CT and ultrasound scanning, is critical.
John H. Lynch +2 more
openaire +3 more sources
New England Journal of Medicine, 2006
In this review we will highlight the recent novel contributions to the treatment of renal cell carcinoma in the fields of anti-angiogenesis, immunotherapeutics, and surgical management. In addition, this review will update recent advances in diagnostic and imaging modalities for renal cell carcinoma and dietary and environmental relationships to the ...
Vincenzi B, Santini D, Tonini G
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In this review we will highlight the recent novel contributions to the treatment of renal cell carcinoma in the fields of anti-angiogenesis, immunotherapeutics, and surgical management. In addition, this review will update recent advances in diagnostic and imaging modalities for renal cell carcinoma and dietary and environmental relationships to the ...
Vincenzi B, Santini D, Tonini G
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Medical Clinics of North America, 1975
The natural history, presenting signs and symptoms, and radiologic evaluation of patients with hypernephroma are reviewed. Radical nephrectomy is the treatment of choice in patients free of metastatic disease. Patients who have evidence of metastatic disease should not be subjected to nephrectomy unless hemorrhage, pain, or some other severe local ...
John A. Libertino, Leonard Zinman
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The natural history, presenting signs and symptoms, and radiologic evaluation of patients with hypernephroma are reviewed. Radical nephrectomy is the treatment of choice in patients free of metastatic disease. Patients who have evidence of metastatic disease should not be subjected to nephrectomy unless hemorrhage, pain, or some other severe local ...
John A. Libertino, Leonard Zinman
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Current Opinion in Oncology, 1991
The behavior of renal cell carcinoma remains one of the most unpredictable of the genitourinary neoplasms. Once this disease has spread beyond the confines of the kidney, it is extremely difficult to control. This year, emphasis has focused on the characteristic cytogenetic and chromosomal changes that are seen in this tumor that help to explain ...
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The behavior of renal cell carcinoma remains one of the most unpredictable of the genitourinary neoplasms. Once this disease has spread beyond the confines of the kidney, it is extremely difficult to control. This year, emphasis has focused on the characteristic cytogenetic and chromosomal changes that are seen in this tumor that help to explain ...
openaire +4 more sources