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Hematology/Oncology Clinics of North America, 2011 Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary cancers and the incidence of RCC has risen steadily. If detected early, RCC is curable by surgery although a minority are at risk of recurrence. Increasing incidental detection and an ageing population has led to active surveillance as an option for patients with small renal
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Current Opinion in Oncology, 2002
Renal cell carcinoma continues to be a difficult malignancy to treat because of its ability to spread asymptomatically and its inherent resistance to conventional chemotherapy. However, molecular genetic studies bring new insights into the pathogenesis of this disorder and may provide new targets against which novel chemotherapeutic agents could be ...
Paul, Godley, Steven W, Kim
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Renal cell carcinoma continues to be a difficult malignancy to treat because of its ability to spread asymptomatically and its inherent resistance to conventional chemotherapy. However, molecular genetic studies bring new insights into the pathogenesis of this disorder and may provide new targets against which novel chemotherapeutic agents could be ...
Paul, Godley, Steven W, Kim
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Hospital Practice, 1987
A doubling in tumor size increases metastases 10-fold and reduces surgical curability drastically. Early diagnosis, abetted by CT and ultrasound scanning, is critical.
J E, Rotolo, W M, O'Brien, J H, Lynch
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A doubling in tumor size increases metastases 10-fold and reduces surgical curability drastically. Early diagnosis, abetted by CT and ultrasound scanning, is critical.
J E, Rotolo, W M, O'Brien, J H, Lynch
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Current Opinion in Oncology, 2001
Several renal cell carcinoma (RCC) prognostic factors show promise, including K1-67, p53/mdm-2, and vascular endothelial growth factor. The combination of increased incidence of RCC and diagnosis during earlier stages has generated interest in local therapeutic options.
P A, Godley, M, Taylor
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Several renal cell carcinoma (RCC) prognostic factors show promise, including K1-67, p53/mdm-2, and vascular endothelial growth factor. The combination of increased incidence of RCC and diagnosis during earlier stages has generated interest in local therapeutic options.
P A, Godley, M, Taylor
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Current Opinion in Oncology, 1993
Renal cell carcinoma remains a challenge for oncologists, with only 20% of patients being cured by surgical removal of the involved kidney and a handful of patients with advanced disease being cured by surgery, immunotherapy, or both. Although advances in early detection, recognition of high-risk groups, and chemotherapy remain disappointing, advances ...
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Renal cell carcinoma remains a challenge for oncologists, with only 20% of patients being cured by surgical removal of the involved kidney and a handful of patients with advanced disease being cured by surgery, immunotherapy, or both. Although advances in early detection, recognition of high-risk groups, and chemotherapy remain disappointing, advances ...
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Current Opinion in Oncology, 2006
In this review we will highlight the recent novel contributions to the treatment of renal cell carcinoma in the fields of anti-angiogenesis, immunotherapeutics, and surgical management. In addition, this review will update recent advances in diagnostic and imaging modalities for renal cell carcinoma and dietary and environmental relationships to the ...
Brian I, Rini +2 more
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In this review we will highlight the recent novel contributions to the treatment of renal cell carcinoma in the fields of anti-angiogenesis, immunotherapeutics, and surgical management. In addition, this review will update recent advances in diagnostic and imaging modalities for renal cell carcinoma and dietary and environmental relationships to the ...
Brian I, Rini +2 more
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Current Opinion in Oncology, 1999
In addition to the known risk factors for renal cell carcinoma, hypertension, obesity, and tobacco use, a diet high in consumption of fried or sautéed meat and the frequent consumption of poultry may increase the risk for renal cell carcinoma. A diet high in consumption of fruits and vegetables appears to have a protective effect. Molecular markers, in
P A, Godley, T E, Stinchcombe
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In addition to the known risk factors for renal cell carcinoma, hypertension, obesity, and tobacco use, a diet high in consumption of fried or sautéed meat and the frequent consumption of poultry may increase the risk for renal cell carcinoma. A diet high in consumption of fruits and vegetables appears to have a protective effect. Molecular markers, in
P A, Godley, T E, Stinchcombe
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The Lancet
The landscape of the management of renal cell carcinoma has evolved substantially in the last decade, leading to improved survival in localised and advanced disease. We review the epidemiology, pathology, and diagnosis of renal cell carcinoma and discuss the evidence for current management strategies from localised to metastatic disease.
Matthew, Young +7 more
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The landscape of the management of renal cell carcinoma has evolved substantially in the last decade, leading to improved survival in localised and advanced disease. We review the epidemiology, pathology, and diagnosis of renal cell carcinoma and discuss the evidence for current management strategies from localised to metastatic disease.
Matthew, Young +7 more
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Current Opinion in Oncology, 2007
This review highlights recent contributions to the biology and treatment of renal cell carcinoma, the expanded use of antiangiogenic agents as well as interest in other inhibitory drug mechanisms. In addition, recent findings are reported on biomarkers which are undergoing investigation as correlative prognostic indicators of either survival or ...
W Kimryn, Rathmell +2 more
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This review highlights recent contributions to the biology and treatment of renal cell carcinoma, the expanded use of antiangiogenic agents as well as interest in other inhibitory drug mechanisms. In addition, recent findings are reported on biomarkers which are undergoing investigation as correlative prognostic indicators of either survival or ...
W Kimryn, Rathmell +2 more
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Southern Medical Journal, 1979
We reviewed the total experience with renal cell carcinoma at West Virginia University Hospital since its opening 15 years ago. While the conclusions are not new, our series of 89 cases reemphasizes the capriciously ubiquitous nature of the disease.
S C, Rochman, J A, Belis, S J, Kandzari
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We reviewed the total experience with renal cell carcinoma at West Virginia University Hospital since its opening 15 years ago. While the conclusions are not new, our series of 89 cases reemphasizes the capriciously ubiquitous nature of the disease.
S C, Rochman, J A, Belis, S J, Kandzari
openaire +2 more sources