Results 31 to 40 of about 1,358,747 (402)

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.

New England Journal of Medicine, 2007
BACKGROUND Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma, a comparison of the drug with interferon alfa in a phase 3 trial is warranted.
R. Motzer, Thomas E. Hutson, P. Tomczak, M. Michaelson, R. Bukowski, O. Rixe, S. Oudard, S. Négrier, C. Szczylik, Sindy T. Kim, I. Chen, P. Bycott, C. Baum, R. Figlin   +13 more
semanticscholar   +1 more source

Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline

Journal of Clinical Oncology, 2022
PURPOSE To provide recommendations for the management of patients with metastatic clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic literature review to obtain evidence to guide treatment recommendations. RESULTS The
W. Rathmell, R. Rumble, P. V. Van Veldhuizen, H. Al-Ahmadie, H. Emamekhoo, R. Hauke, A. Louie, M. Milowsky, A. Molina, T. Rose, S. Siva, Nicholas G Zaorsky, Tian Zhang, R. Qamar, Terry M Kungel, Bryan Lewis, E. Singer   +16 more
semanticscholar   +1 more source

Sorafenib in advanced clear-cell renal-cell carcinoma.

New England Journal of Medicine, 2007
BACKGROUND We conducted a phase 3, randomized, double-blind, placebo-controlled trial of sorafenib, a multikinase inhibitor of tumor-cell proliferation and angiogenesis, in patients with advanced clear-cell renal-cell carcinoma.
B. Escudier, T. Eisen, W. Stadler, C. Szczylik, S. Oudard, M. Siebels, S. Négrier, C. Chevreau, E. Solska, A. Desai, F. Rolland, T. Demkow, Thomas E. Hutson, M. Gore, S. Freeman, B. Schwartz, M. Shan, R. Simantov, R. Bukowski   +18 more
semanticscholar   +1 more source

The Labyrinth of Renal Cell Carcinoma [PDF]

Cancers, 2020
Renal cell carcinoma (RCC) ranks in the top-ten list of malignancies both in males and females [...]
Claudia Manini, José I. López
openaire   +4 more sources

Diffuse thyroid metastases and bilateral internal jugular vein tumor thrombus from renal cell cancer. [PDF]

, 2016
Renal cell cancer rarely metastasizes to the thyroid gland, and it has been reported to present as a solitary mass. We present a case of diffuse thyroid cancer metastases from renal cell cancer.
Jha, Priyanka, Mari-Aparici, Carina, Shekhar, Mallika, Wan, Jennifer   +3 more
core   +1 more source

Avelumab plus Axitinib versus Sunitinib for Advanced Renal‐Cell Carcinoma

New England Journal of Medicine, 2019
BACKGROUND In a single‐group, phase 1b trial, avelumab plus axitinib resulted in objective responses in patients with advanced renal‐cell carcinoma. This phase 3 trial involving previously untreated patients with advanced renal‐cell carcinoma compared ...
R. Motzer, K. Penkov, J. Haanen, B. Rini, L. Albiges, M. Campbell, B. Venugopal, C. Kollmannsberger, S. Négrier, M. Uemura, J. Lee, A. Vasiliev, W. Miller, H. Gurney, M. Schmidinger, J. Larkin, M. Atkins, J. Bedke, B. Alekseev, Jing Wang, M. Mariani, P. Robbins, A. Chudnovsky, C. Fowst, S. Hariharan, B. Huang, A. di Pietro, T. Choueiri   +27 more
semanticscholar   +1 more source

Epidemiology of Renal Cell Carcinoma

World Journal of Oncology, 2020
Though renal cell carcinoma (RCC) accounts for 2% of global cancer diagnoses and deaths, it has more than doubled in incidence in the developed world over the past half-century, and today is the ninth most common neoplasm in the United States (US). While
S. Padala, A. Barsouk, K. Thandra, Kalyan Saginala, A. Mohammed, Anusha Vakiti, Prashanth Rawla, Alexander Barsouk   +7 more
semanticscholar   +1 more source

Synchronous bilateral renal cell carcinomas with differing histologies

IJU Case Reports, 2020
Introduction Bilateral renal cell carcinomas with different histological types are rare. We report herein the first description of bilateral renal carcinomas with clear cell renal cell carcinoma and mucinous tubular and spindle cell carcinoma occurring ...
Ryu Shigehisa, Takashi Karashima, Shu Kobayashi, Kaya Atagi, Daigo Takemori, Hideo Fukuhara, Satoshi Fukata, Ichiro Murakami, Naoto Kuroda, Keiji Inoue   +9 more
doaj   +1 more source

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.

New England Journal of Medicine, 2007
BACKGROUND Interferon alfa is widely used for metastatic renal-cell carcinoma but has limited efficacy and tolerability. Temsirolimus, a specific inhibitor of the mammalian target of rapamycin kinase, may benefit patients with this disease.
G. Hudes, M. Carducci, P. Tomczak, J. Dutcher, R. Figlin, A. Kapoor, E. Starosławska, J. Sosman, D. McDermott, I. Bodrogi, Z. Kovačević, V. Lesovoy, I. Schmidt-Wolf, O. Barbarash, E. Gokmen, T. O'Toole, S. Lustgarten, L. Moore, R. Motzer   +18 more
semanticscholar   +1 more source

A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population

Nature Communications, 2022
Clear cell renal cell carcinoma (ccRCC) is a common and aggressive subtype of renal cancer. Here we conduct a comprehensive proteogenomic analysis of 232 tumor and adjacent non-tumor tissue pairs from Chinese ccRCC patients.
Y. Qu, Jinwen Feng, Xiaohui Wu, Lin Bai, Wenhao Xu, Lingli Zhu, Yang Liu, Fujiang Xu, Xuan Zhang, Guojian Yang, Jiacheng Lv, Xiu Chen, G. Shi, Hong-kai Wang, D. Cao, Hang Xiang, Lingling Li, S. Tan, H. Gan, Meng Sun, J. Qiu, Hailiang Zhang, Jianyuan Zhao, Dingwei Ye, C. Ding   +24 more
semanticscholar   +1 more source