Results 31 to 40 of about 1,140,223 (331)

Avelumab plus Axitinib versus Sunitinib for Advanced Renal‐Cell Carcinoma

New England Journal of Medicine, 2019
BACKGROUND In a single‐group, phase 1b trial, avelumab plus axitinib resulted in objective responses in patients with advanced renal‐cell carcinoma. This phase 3 trial involving previously untreated patients with advanced renal‐cell carcinoma compared ...
R. Motzer, K. Penkov, J. Haanen, B. Rini, L. Albiges, M. Campbell, B. Venugopal, C. Kollmannsberger, S. Négrier, M. Uemura, J. Lee, A. Vasiliev, W. Miller, H. Gurney, M. Schmidinger, J. Larkin, M. Atkins, J. Bedke, B. Alekseev, Jing Wang, M. Mariani, P. Robbins, A. Chudnovsky, C. Fowst, S. Hariharan, B. Huang, A. di Pietro, T. Choueiri   +27 more
semanticscholar   +1 more source

Renal Cell Carcinoma [PDF]

Journal of Urology, 1982
The clinical presentation of renal cell carcinoma is often diverse and outcome is notoriously difficult to predict. The only therapy for renal cell carcinoma with curative potential is radical surgery for patients presenting with locoregional disease.
openaire   +6 more sources

Synchronous bilateral renal cell carcinomas with differing histologies

IJU Case Reports, 2020
Introduction Bilateral renal cell carcinomas with different histological types are rare. We report herein the first description of bilateral renal carcinomas with clear cell renal cell carcinoma and mucinous tubular and spindle cell carcinoma occurring ...
Ryu Shigehisa, Takashi Karashima, Shu Kobayashi, Kaya Atagi, Daigo Takemori, Hideo Fukuhara, Satoshi Fukata, Ichiro Murakami, Naoto Kuroda, Keiji Inoue   +9 more
doaj   +1 more source

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.

New England Journal of Medicine, 2007
BACKGROUND Interferon alfa is widely used for metastatic renal-cell carcinoma but has limited efficacy and tolerability. Temsirolimus, a specific inhibitor of the mammalian target of rapamycin kinase, may benefit patients with this disease.
G. Hudes, M. Carducci, P. Tomczak, J. Dutcher, R. Figlin, A. Kapoor, E. Starosławska, J. Sosman, D. McDermott, I. Bodrogi, Z. Kovačević, V. Lesovoy, I. Schmidt-Wolf, O. Barbarash, E. Gokmen, T. O'Toole, S. Lustgarten, L. Moore, R. Motzer   +18 more
semanticscholar   +1 more source

Epidemiology and Prevention of Renal Cell Carcinoma

Cancers, 2022
Simple Summary The incidence of renal cell carcinoma (RCC) rises globally with the highest rates in developed countries. This indicates not only the impact of advanced imaging, but also an increased prevalence of modifiable risk factors such as smoking ...
Tomoyuki Makino, S. Kadomoto, K. Izumi, A. Mizokami   +3 more
semanticscholar   +1 more source

Association of dyslipidemia with renal cell carcinoma: a 1∶2 matched case-control study. [PDF]

PLoS ONE, 2013
Abnormal serum lipid profiles are associated with the risk of some cancers, but the direction and magnitude of the association with renal cell carcinoma is unclear.
Chunfang Zhang, Luping Yu, Tao Xu, Yichang Hao, Xiaowei Zhang, Zhenhua Liu, Yunbei Xiao, Xiaofeng Wang, Qiang Zeng   +8 more
doaj   +1 more source

COMPREHENSIVE MOLECULAR CHARACTERIZATION OF CLEAR CELL RENAL CELL CARCINOMA

Nature, 2013
Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, PBRM1).
The Cancer Genome Atlas Research Network
semanticscholar   +1 more source

A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population

Nature Communications, 2022
Clear cell renal cell carcinoma (ccRCC) is a common and aggressive subtype of renal cancer. Here we conduct a comprehensive proteogenomic analysis of 232 tumor and adjacent non-tumor tissue pairs from Chinese ccRCC patients.
Y. Qu, Jinwen Feng, Xiaohui Wu, Lin Bai, Wenhao Xu, Lingli Zhu, Yang Liu, Fujiang Xu, Xuan Zhang, Guojian Yang, Jiacheng Lv, Xiu Chen, G. Shi, Hong-kai Wang, D. Cao, Hang Xiang, Lingling Li, S. Tan, H. Gan, Meng Sun, J. Qiu, Hailiang Zhang, Jianyuan Zhao, Dingwei Ye, C. Ding   +24 more
semanticscholar   +1 more source

Case of hereditary papillary renal cell carcinoma [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2012
Renal cell carcinoma is the most common type of renal malignancy and it originates from the renal tubular epithelium. Due to the diversity in the histopathological and molecular characteristics, it is typically subclassified into five different ...
Sadaf Mustafa, Nima Jadidi, Sheila F. Faraj, Ronald Rodriguez   +3 more
doaj   +1 more source

Expression of lactate dehydrogenase C correlates with poor prognosis in renal cell carcinoma

Tumor Biology, 2017
Lactate dehydrogenase C is an isoenzyme of lactate dehydrogenase and a member of the cancer–testis antigens family. In this study, we aimed to investigate the expression and functional role of lactate dehydrogenase C and its basic mechanisms in renal ...
Yibo Hua, Chao Liang, Jundong Zhu, Chenkui Miao, Yajie Yu, Aimin Xu, Jianzhong Zhang, Pu Li, Shuang Li, Meiling Bao, Jie Yang, Chao Qin, Zengjun Wang   +12 more
doaj   +1 more source