Results 71 to 80 of about 1,358,747 (402)

LncRNA UCA1 promotes renal cell carcinoma proliferation through epigenetically repressing p21 expression and negatively regulating miR-495

open access: yesTumor Biology, 2017
Long non-coding RNAs have recently emerged as important regulators in the pathogenesis and progression of cancers. The long non-coding RNA urothelial carcinoma–associated 1 is reportedly upregulated and functions as an oncogene in some tumors.
Yun Lu   +8 more
doaj   +1 more source

Arteriography during ex vivo renal perfusion A complication [PDF]

open access: yes, 1973
A case of bilateral renal-cell carcinoma unsuccessfully treated with bench surgery is reported. The reason for failure was apparently the toxicity of the contrast media used during the ex vivo arteriographic studies ...
Alfidi   +20 more
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Unusual head and neck presentation of metastatic renal cell carcinoma

open access: yesOtolaryngology Case Reports, 2023
Skull base metastasis from renal cell carcinoma are exceedingly rare. Though renal cell carcinoma often presents at an advanced stage and with metastasis, signs and symptoms of skull base involvement would rarely suggest renal cell carcinoma.
Kyle J. Kozak   +2 more
doaj  

Renal cell carcinoma with melanin pigment

open access: yesIndian Journal of Urology, 2010
The incidence of renal cell carcinoma has been steadily increasing. There are several morphological types of renal cell carcinoma. Recognizing histologic patterns of renal cell carcinoma is important for correct diagnosis and subsequent medical care for ...
Jayaprakash Shetty   +2 more
doaj   +1 more source

Instance-based Vision Transformer for Subtyping of Papillary Renal Cell Carcinoma in Histopathological Image [PDF]

open access: yesarXiv, 2021
Histological subtype of papillary (p) renal cell carcinoma (RCC), type 1 vs. type 2, is an essential prognostic factor. The two subtypes of pRCC have a similar pattern, i.e., the papillary architecture, yet some subtle differences, including cellular and cell-layer level patterns.
arxiv  

Pazopanib versus sunitinib in metastatic renal-cell carcinoma.

open access: yesNew England Journal of Medicine, 2013
BACKGROUND Pazopanib and sunitinib provided a progression-free survival benefit, as compared with placebo or interferon, in previous phase 3 studies involving patients with metastatic renal-cell carcinoma.
R. Motzer   +24 more
semanticscholar   +1 more source

Chromophobe Renal Cell Carcinoma [PDF]

open access: yes, 2013
Renal cell carcinoma is the most common neoplasm of the kidney comprised of different histological variants. Chromophobe renal cell carcinoma (ChRCC) is a rare subtype of renal cell carcinoma (RCC) mainly diagnosed in the sixth decade of life.
Huddedar, AD   +3 more
core   +1 more source

MiT Family Translocation Renal Cell Carcinoma: from the Early Descriptions to the Current Knowledge [PDF]

open access: yes, 2019
The new category of MiT family translocation renal cell carcinoma has been included into the World Health Organization (WHO) classification in 2016.
Brunelli, Matteo   +4 more
core   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

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