Results 161 to 170 of about 2,205,306 (373)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

EXPERIMENTAL STUDY OF CHANGES IN THE RENAL CIRCULATION SUBSEQUENT TO THE URETERO-ENTEROSTOMY, BY MEANS OF THE INJECTION OF THE INDIAN INK

, 1956
Satoru Murakami
openalex   +2 more sources

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang, Yuanhao Zhou, Qingyuan Wu, Yishu Li, Yilin Huang, Kexin Yu, Ping Li, Zhenye Lv, Haotian Liu, Hai Zou, Huiyu Liu, Xiaozhou Mou   +11 more
wiley   +1 more source

Cardiac Biomarkers and Risk of Atrial Fibrillation in Chronic Kidney Disease: The CRIC Study. [PDF]

, 2019
Background We tested associations of cardiac biomarkers of myocardial stretch, injury, inflammation, and fibrosis with the risk of incident atrial fibrillation (AF) in a prospective study of chronic kidney disease patients.
Anderson, Amanda H, Appel, Lawrence J, Bansal, Nisha, Christenson, Rob, deFilippi, Christopher R, Deo, Rajat, Feldman, Harold I, Floyd, James S, Go, Alan S, He, Jiang, Kusek, John W, Ky, Bonnie, Lamprea‐Montealegre, Julio A, Lash, James P, Rahman, Mahboob, Rao, Panduranga S, Seliger, Stephen L, Shafi, Tariq, Shlipak, Michael G, Soliman, Elsayed Z, Townsend, Raymond R, Wolf, Myles S, Zelnick, Leila R   +22 more
core  

Pharmacological contributions on diuresis and the renal circulation

, 1959
中澤 與四郎, 上野 昭, 酒井 潔
openalex   +2 more sources

beta‐Adrenoceptor‐blocking agents and the kidney: effect of nadolol and propranolol on the renal circulation. [PDF]

, 1979
Hollenberg Nk, DF Adams, DN McKinstry, GH Williams, LJ Borucki, John M. Sullivan   +5 more
openalex   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source

The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]

, 2013
Abdala, Ana P, Burchell, Amy, Engleman, Zoar J, Fudim, Marat, Gourine, Alexander V, Hart, Emma C J, Lobo, Mel, Marina, Nepthali, McBryde, Fiona D, Nightingale, Angus, Patel, Nik, Paton, Julian F R, Ratcliffe, Laura E K, Sobotka, Paul A   +13 more
core   +1 more source

RENAL ARTERIOGRAPHY DURING EXTRACORPOREAL CIRCULATION IN DOGS, WITH A PRELIMINARY REPORT UPON THE EFFECTS OF LOW MOLECULAR WEIGHT DEXTRAN

, 1961
W Finsterbusch, David M. Long, Robert D. Sellers, Kurt Amplatz, C. Walton Lillehei   +4 more
openalex   +1 more source

Resident Macrophage‐Orchestrated Immune and Fibroblast Interactions in Immune Checkpoint Inhibitor‐Associated Nephrotoxicity

Advanced Science, EarlyView.
Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma, Yang Chen, Qinfan Yao, Yuxi Wang, Nan Ouyang, Fei Han, Guzong Wang, Meifang Wang, Yuan Yuan, Jianghua Chen, Jianzhen Shan, Dajin Chen   +11 more
wiley   +1 more source