Results 161 to 170 of about 2,167,615 (375)
STUDIES ON THE EFFECTS OF WATER, PAH, GLUCOSE AND SEVERAL DRUGS ON RENAL CIRCULATION AND METABOLISM
Takao Ikeda
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This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu+7 more
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This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren+11 more
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Hypertension as a Presentation of Bilateral Intrarenal Arateriovenous Malformation
Congenital arteriovenous malformations are rare lesions of the kidneys. The first case of bilateral renal arteriovenous malformations was described in 1987.
El-Lozi Mohamed, Hadad A
doaj
Pharmacological contributions on diuresis and the renal circulation
中澤 與四郎, 上野 昭, 酒井 潔
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beta‐Adrenoceptor‐blocking agents and the kidney: effect of nadolol and propranolol on the renal circulation. [PDF]
Hollenberg Nk+5 more
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Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod+9 more
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Disappearance of Bradykinin in the Renal Circulation of Dogs: EFFECTS OF KININASE INHIBITION
A. Nasjletti+2 more
semanticscholar +1 more source
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni+12 more
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