Results 171 to 180 of about 2,140,639 (395)
The most severe complication of yttrium-90 therapy is gastrointestinal ulceration caused by extrahepatic dispersion of microspheres. Standard pretreatment planning requires extensive angiographic evaluation of the hepatic circulation and embolization of ...
Justin Smith+6 more
doaj +1 more source
REACTIVITY OF RENAL AND SYSTEMIC CIRCULATIONS TO VASOCONSTRICTOR AGENTS IN NORMOTENSIVE AND HYPERTENSIVE SUBJECTS* [PDF]
Ervin A. Gombos+5 more
openalex +1 more source
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo+10 more
wiley +1 more source
our findings robustly demonstrate that our constructed prlncRNA signature could serve as an efficient indicator of prognosis, immunotherapy response, and chemosensitivity for HNSCC patients. Abstract Background Pyroptosis plays an essential function in carcinogenesis and the antitumor immune response.
Chongchang Zhou+6 more
wiley +1 more source
Hepatorenal syndrome is a condition that occurs in patients with chronic liver disease characterized by portal hypertension and it is distinguished by the deterioration of renal function and marked abnormalities in blood circulation, with activation of ...
Raysa Garay Padrón+2 more
doaj
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang+4 more
wiley +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan+4 more
wiley +1 more source
Metabolism and secretion of retinol transport complex in acute renal failure
Tissue uptake and distribution of retinol from circulatory vitamin A transport complex was studied in order to determine the origin of the increased serum retinol in rats with short-term acute renal failure.
TH Gerlach, MH Zile
doaj
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang+6 more
wiley +1 more source
Introduction. The need to develop effective methods of renal protection during cardiac surgical interventions is dictated by the progressive increase of acute kidney injury (CS-AKI) in children, which is associated with immaturity of renal function and ...
P. V. Zinchuk+3 more
doaj +1 more source