Results 191 to 200 of about 2,140,639 (395)

Severe Rhabdomyolysis from Pharmacokinetic Interaction of Statin in Patient with Diabetic Nephropathy: A Case Report

open access: yesSiriraj Medical Journal, 2015
Rhabdomyolysis is a potentially life-threatening syndrome characterized by muscle necrosis and the release of intracellular muscle contents into systemic circulation.
Teerapong Monmaturapoj
doaj  

The impact of delayed adjuvant chemotherapy on survival in gastric cancer patients with and without preoperative chemotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Delayed initiation of adjuvant chemotherapy (AC) is associated with significantly poorer postoperative survival in patients with gastric cancer, irrespective of whether preoperative chemotherapy was administered. These findings emphasize the importance of timely AC initiation to improve long‐term outcomes in this patient population.
Masataka Shimonosono   +6 more
wiley   +1 more source

Chronic glomerulonephritis and pregnancy

open access: yesТерапевтический архив, 2004
Aim. To clarify factors of risk for unfavourable variants of gestational chronic glomerulonephritis (CGN) and poor pregnancy outcomes in CGN; to determine prognostic implications of changes in some renal and uteroplacental indices.
V A Rogov   +6 more
doaj  

Enhancing SDT Efficacy of Doxorubicin‐Loaded Sonosensitizer Micelles to Overcome Resistance of Cancer Therapy by Optimizing Acoustic Parameters

open access: yesAggregate, EarlyView.
The study reveals that optimizing various parameters of sonodynamic therapy (SDT), including the functional characteristics of sonosensitizers and the optimization of acoustic parameters, can significantly enhance SDT therapeutic efficacy. When combined with chemotherapy, this approach effectively overcomes tumor resistance and induces antitumor immune
Zhuoran Gong   +6 more
wiley   +1 more source

Evaluation of sweating responses in patients with systemic connective tissue disorders using the quantitative sudomotor axon reflex test

open access: yesJournal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 208-216, December 2022., 2022
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida   +5 more
wiley   +1 more source

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

open access: yesAngewandte Chemie, EarlyView.
A strategy for the conditional activation of therapeutic proteins utilizing removable peptide nucleic acid (PNA) masking groups is presented. Site‐specific installation of “Lock”‐PNAs containing a cleavage thioester linkage enabled steric blockage of receptor binding sites.
Bengt H. Gless   +6 more
wiley   +2 more sources

Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1287-1296, December 2022., 2022
Abstract Background Type 2 diabetes mellitus (T2DM) patients may have cardiac remodeling and dysfunction from the early stage of disease. This study aimed to determine the association between cystatin C (CysC) and early cardiac functional or structural impairment in T2DM patients without renal dysfunction.
Zhuoshan Huang   +10 more
wiley   +1 more source

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