Surgical and diagnostic management challenges of giant Wilms tumor with intracardial and IVC thrombus extension in a 3-year-old: A rare case from a resource-limited facility involving global and local pediatric surgical teams. [PDF]
Shadrack M+5 more
europepmc +1 more source
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad+9 more
wiley +1 more source
Clarifying endothelin type B receptor function [PDF]
Pollock, D.M., Schneider, M.P.
core +1 more source
Long‐term immunosuppression of rabbits through oral tacrolimus administration
Oral gavage of rabbits with 1.5 mg/kg/d of tacrolimus allows for an efficient long‐term (1 year) immunosuppression with minimal side effects and no loss of animals. lmmunosuppressed rabbits are a convenient animal model to investigate the long‐term efficacy of human allografts in vivo.
Alexane Thibodeau+4 more
wiley +1 more source
Mapping the hemodynamic effects of terlipressin in patients with hepatorenal syndrome using advanced magnetic resonance imaging. [PDF]
Danielsen KV+10 more
europepmc +1 more source
Strategies for optimization of hypoglycemia rat models
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher+4 more
wiley +1 more source
Periodontal disease and chronic kidney disease: mechanistic insights and novel therapeutic perspectives. [PDF]
Li S+7 more
europepmc +1 more source
Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang+5 more
wiley +1 more source
Crosstalk between lung and extrapulmonary organs in sepsis-related acute lung injury/acute respiratory distress syndrome. [PDF]
Li B+12 more
europepmc +1 more source