Endothelium derived signaling mechanisms play an important role in regulating vascular tone and endothelial dysfunction is often found in hypertension.
Søs U. Stannov +4 more
doaj +1 more source
Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane [PDF]
Despite being engineered to avoid renal clearance, many cationic polymer (polycation)-based siRNA nanoparticles that are used for systemic delivery are rapidly eliminated from the circulation.
Andrews +26 more
core +3 more sources
Severe acute kidney injury associated with immersion into seawater
Near drowning is an important, but rarely reported precipitant of acute kidney injury (AKI). The underlying pathophysiology is thought to be ischaemic kidney injury, but diagnostic uncertainty has arisen due to reports of isolated AKI in the absence of ...
Ian R. Logan, Alison L. Brown
doaj +1 more source
Does kidney function matter in pulmonary thromboembolism management?
Cardiovascular circulation and kidney function are closely interrelated. The impairment of renal function is a well-known hazard of increased mortality and morbidity of patients with heart failure or coronary artery disease. Acute pulmonary embolism (APE)
Magdalena Pływaczewska +2 more
doaj +1 more source
Impaired endothelial function of the retinal vasculature in hypertensive patients [PDF]
<p><b>Background and Purpose:</b> Arterial hypertension constitutes a central factor in the pathogenesis of stroke. We examined endothelial function of the retinal vasculature as a model of the cerebral circulation.</p> <p ...
Delles, C. +5 more
core +1 more source
Treatment of atherosclerotic renovascular hypertension: review of observational studies and a meta-analysis of randomized clinical trials. [PDF]
open9Atherosclerotic renal artery stenosis can cause ischaemic nephropathy and arterial hypertension. We herein review the observational and randomized clinical trials (RCTs) comparing medical and endovascular treatment for control of hypertension and ...
Caielli, P +8 more
core +1 more source
Troponins, Acute Coronary Syndrome and Renal Disease: From Acute Kidney Injury Through End-stage Kidney Disease [PDF]
The diagnosis of acute coronary syndromes (ACS) is heavily dependent on cardiac biomarker assays, particularly cardiac troponins. ACS, particularly non-ST segment elevation MI, are more common in patients with acute kidney injury, chronic kidney disease (
Banerjee, A, Banerjee, D, Ferrett, C
core +2 more sources
Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection. [PDF]
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose and predict cardiac allograft rejection, we analyzed 250 blood samples from heart transplant recipients with and without acute rejection (AR) and with ...
Hsieh, Szu-Chuan +9 more
core +5 more sources
Prostacyclin is an in vivo bioactive substance that regulates renal blood flow (RBF). Information regarding how epoprostenol, a prostacyclin preparation, affects RBF in dogs is lacking.
Kiwamu Hanazono +6 more
doaj +1 more source
Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis [PDF]
Hepatorenal syndrome (HRS) is a serious complication of end-stage liver disease, occurring mainly in patients with advanced cirrhosis and ascites, who have marked circulatory dysfunction,1 as well as in patients with acute liver failure.2 In spite of its
Angeli P +21 more
core +4 more sources

