Results 101 to 110 of about 299,030 (338)
Advanced Science, EarlyView.Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian +7 more
wiley +1 more source
The Multidisciplinary Approach to Renal Denervation: Current Evidences and Open Questions [PDF]
European Medical Journal Nephrology, 2014 Renal denervation (RD) is a new clinical procedure which aims to treat resistant hypertensive patients. As with every new technology introduced into the clinical setting, many aspects were not explored sufficiently in order to be implemented into routine
Sara Samoni +10 more
doaj
Reversible Fluindione-Induced Chronic Interstitial Nephritis
Case Reports in Nephrology, 2016 Fluindione is well known to induce acute drug-induced interstitial nephritis (IN). Most cases occurred soon after the onset of treatment. We report a unique case of severe subacute fluindione-induced IN diagnosed 2 years after the treatment was begun ...
Thomas Crepin +5 more
doaj +1 more source
Stigma and related factors among renal dialysis patients in China. [PDF]
Front Psychiatry, 2023 Li B, Liu D, Zhang Y, Xue P.
europepmc +1 more source
Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]
, 2019 Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi +2 more
core
Advanced Science, EarlyView.SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv +16 more
wiley +1 more source
Advanced Science, EarlyView.Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin +18 more
wiley +1 more source
Social Determinants of Health Impacting Access to Renal Dialysis for Racial/Ethnic Minorities. [PDF]
Cureus, 2023 Mercen JL +10 more
europepmc +1 more source
Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding
Advanced Science, EarlyView.Conventional poly(ethylene glycol) (PEG) is commonly applied in biomedicine, but is now known to induce antibody formation. Here, it is shown that the development of “randomized PEG” (rPEG) featuring glycidyl methyl ether (GME) comonomers decreased antibody binding.
Mareike Deuker +5 more
wiley +1 more source
Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units - A high risk community-hospital interface. [PDF]
J Infect, 2021 Li KK +42 more
europepmc +2 more sources