Results 121 to 130 of about 1,562,538 (380)
PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury
Advanced Science, EarlyView.Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan +17 more
wiley +1 more source
Acute interstitial nephritis, a rare complication of Giardiasis
Clinics and Practice, 2011 Acute interstitial nephritis is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions.
Antonio De Pascalis, Erasmo Buongiorno
doaj +1 more source
Thrice weekly nocturnal in-centre haemodiafiltration: a 2-year experience [PDF]
, 2015 Background: Adequate control of plasma phosphate without phosphate binders is difficult to achieve on a thrice-weekly haemodialysis schedule. The use of quotidian nocturnal dialysis is effective but not practical in the in-centre setting.
Dey, V., Hair, M., Spalding, E. M.
core +1 more source
Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment
Advanced Science, EarlyView.A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen +7 more
wiley +1 more source
Immunoglobulin A Nephropathy. Recurrence After Renal Transplantation
Frontiers in Immunology, 2019 IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide. The disease generally runs an indolent course but may lead to ESRD in 20–30% of patients in 20 years or more after diagnosis.
Gabriella Moroni +5 more
doaj +1 more source
A Primer on Quality Assurance and Performance Improvement for Interprofessional Chronic Kidney Disease Care: A Path to Joint Commission Certification. [PDF]
, 2019 Interprofessional care for chronic kidney disease facilitates the delivery of high quality, comprehensive care to a complex, at-risk population. Interprofessional care is resource intensive and requires a value proposition. Joint Commission certification
Awdishu, Linda +4 more
core +1 more source
Advanced Science, EarlyView.The role of splicing factor 3A subunit 3 (SF3A3) in driving endometrial cancer (EC) progression and potential therapeutic interventions. SF3A3, a core component of the U2 small nuclear ribonucleoprotein (U2 snRNP), is upregulated in endometrial cancer (EC) and promotes tumor growth and cisplatin resistance. RNA‐binding protein immunoprecipitation (RIP)
Wei Yu +13 more
wiley +1 more source
Renal Replacement TherapyBackground In Japan dialyzers are classified as type I, II, III, IV, or V on the basis of the β 2-microglobulin clearance. In 2023, Type V dialyzers were defined as super high-flux membrane dialyzers.
Masanori Abe +5 more
doaj +1 more source
Membranous Nephropathy (MN) Recurrence After Renal Transplantation
Frontiers in Immunology, 2019 Primary membranous nephropathy (MN) is a frequent cause of NS in adults. In native kidneys the disease may progress to ESRD in the long term, in some 40–50% of untreated patients.
Patrizia Passerini +5 more
doaj +1 more source
Lack of evidence does not justify neglect. how can we address unmet medical needs in calciphylaxis [PDF]
, 2016 Calcific uraemic arteriolopathy (CUA), or calciphylaxis, is a rare disease predominantly occurring in comorbidity with dialysis. Due to the very low frequency of CUA, prospective studies on its management are lacking and even anecdotal reports on ...
Brandenburg, Vincent Matthias +14 more
core +1 more source