Results 191 to 200 of about 299,030 (338)

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

open access: yesExploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren   +15 more
wiley   +1 more source

Role of Local Renin Angiotensin System Activation on Blood Pressure and Residual Renal Function in Peritoneal Dialysis Patients

open access: diamond, 2019
Tolga Yıldırım   +8 more
openalex   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

open access: yesFood Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu   +8 more
wiley   +1 more source

Cardiopulmonary Exercise Test Parameters among Dialysis Patients with End-Stage Renal Disease. [PDF]

open access: green, 2023
Alireza Eslaminejad   +3 more
openalex  

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