Results 121 to 130 of about 1,236,008 (363)

Incidence of Side Effects Associated With Acetaminophen in People Aged 65 Years or More: A Prospective Cohort Study Using Data From the Clinical Practice Research Datalink

open access: yesArthritis Care &Research, EarlyView.
Objective The main objective of this study is to examine the safety of oral acetaminophen at its therapeutic dose in adults aged ≥65 years. Methods This population‐based cohort study used the Clinical Practice Research Datalink‐Gold data. Participants were aged ≥65 years registered with a UK general practice for at least 12 months between 1998 and 2018.
Jaspreet Kaur   +5 more
wiley   +1 more source

Comparison between Tc-99m DMSA and Renal Ultrasonography for the Evaluation of Renal Scarring and Function Loss in Children with Spina Bifida

open access: yesİstanbul Medical Journal, 2017
Objective: We aimed to compare the sensitivity of ultrasonography (US) and Dimercaptosuccinic acid (DMSA) scintigraphy in evaluating renal scarring and kidney function in children with spina bifida (SB).Methods: The study group comprised 100 patients (51
Ebru Özgönenel   +8 more
doaj   +1 more source

The effect of graft function on FK506 plasma levels, dosages, and renal function, with particular reference to the liver [PDF]

open access: yes, 1991
Plasma FK506 was studied in 49 liver, 13 heart, 3 double-lung or heart-lung, and 21 kidney recipients. The levels were correlated with the drug doses used, kidney function, and liver function.
Abu-Elmagd, K   +9 more
core   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

open access: yesAdvanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang   +6 more
wiley   +1 more source

Sequential Variations of Renal Function Parameters and Oxidative Status after Surgical Ablation of 5/6 of Renal Mass in Wistar Rats

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: In rats with subtotal nephrectomy occurs progressive changes on renal function, oxidative damage to lipids and proteins and antioxidant defenses.
Miriela Betancourt Valladares   +4 more
doaj  

Measurement of glomerular filtration rate in patients undergoing obesity surgery

open access: yesBMC Nephrology, 2018
Background Most studies on obesity surgery have measured renal function using the estimated GFR. However, due to the reduction of muscle mass, and therefore creatinine that accompanies weight loss, such measures can falsely suggest an improvement in ...
Ling L. Chuah   +7 more
doaj   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Will Incremental Hemodialysis Preserve Residual Function and Improve Patient Survival? [PDF]

open access: yes, 2014
The progressive loss of residual renal function in peritoneal dialysis patients is associated with increased mortality. It has been suggested that incremental dialysis may help preserve residual renal function and improve patient survival. Residual renal
Davenport, A
core   +1 more source

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