Results 141 to 150 of about 12,896,191 (434)

Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis [PDF]

open access: yes, 2009
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities.
Clatworthy, Menna R   +4 more
core   +1 more source

Unsupervised Community Detection with a Potts Model Hamiltonian, an Efficient Algorithmic Solution, and Applications in Digital Pathology [PDF]

open access: yesarXiv, 2020
Unsupervised segmentation of large images using a Potts model Hamiltonian is unique in that segmentation is governed by a resolution parameter which scales the sensitivity to small clusters. Here, the input image is first modeled as a graph, which is then segmented by minimizing a Hamiltonian cost function defined on the graph and the respective ...
arxiv  

The effect of graft function on FK506 plasma levels, dosages, and renal function, with particular reference to the liver [PDF]

open access: yes, 1991
Plasma FK506 was studied in 49 liver, 13 heart, 3 double-lung or heart-lung, and 21 kidney recipients. The levels were correlated with the drug doses used, kidney function, and liver function.
Abu-Elmagd, K   +9 more
core   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun   +8 more
wiley   +1 more source

Impaired renal function and increased urinary isoprostane excretion in Ghanaian women with pre-eclampsia

open access: yesResearch and Reports in Tropical Medicine, 2013
Paul Winston Tetteh,1,4 Charles Antwi-Boasiako,1 Ben Gyan,3 Daniel Antwi,1 Festus Adzaku,1 Kwame Adu-Bonsaffoh,1,2 Samuel Obed21Department of Physiology, 2Department of Obstetrics and Gynecology, University of Ghana Medical School, Accra, Ghana ...
Tetteh PW   +6 more
doaj  

Global Sensitivity Analysis in a Mathematical Model of the Renal Interstitium [PDF]

open access: yesarXiv, 2016
The pressure in the renal interstitium is an important factor for normal kidney function. Here we develop a computational model of the rat kidney and use it to investigate the relationship between arterial blood pressure and interstitial fluid pressure. In addition, we investigate how tissue flexibility influences this relationship.
arxiv  

Will Incremental Hemodialysis Preserve Residual Function and Improve Patient Survival? [PDF]

open access: yes, 2014
The progressive loss of residual renal function in peritoneal dialysis patients is associated with increased mortality. It has been suggested that incremental dialysis may help preserve residual renal function and improve patient survival. Residual renal
Davenport, A
core   +1 more source

Effects of saline, mannitol, and furosemide on acute decreases in renal function induced by radiocontrast agents.

open access: yesNew England Journal of Medicine, 1994
BACKGROUND Injections of radiocontrast agents are a frequent cause of acute decreases in renal function, occurring most often in patients with chronic renal insufficiency and diabetes mellitus.
R. Solomon   +4 more
semanticscholar   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp   +8 more
wiley   +1 more source

The prevalence, clinical features, and long-term outcome of patients with primary Sjögren’s syndrome with renal involvement

open access: yesScientific Reports
This multicenter, retrospective longitudinal study identified primary Sjögren’s syndrome (pSS) patients with clinically significant renal involvement, and analyzed factors associated with predisposition.
Howook Jeon   +7 more
doaj   +1 more source

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