Tissue typing by unidirectional mixed lymphocyte culture. 3. The relationship of in vitro lymphocyte compatibility to renal allograft rejection [PDF]
We applied unidirectional MLC test to renal allograft in dogs, and investigated the correlation between the growth rates of MLC reaction and the intensity of rejection of the kidney transplants or the postoperative renal function.
Tsunemitsu, Kensuke
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Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N. +5 more
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Background: The pleiotropic efficacy of SGLT2is in patients with different eGFR levels has not been well-understood. This systematic review and meta-analysis assessed the disparities in the efficacy and safety of SGLT2i treatment across stratified renal ...
Suiyuan Hu +6 more
doaj +1 more source
Renal Sympathetic Denervation: Renal Function Concerns [PDF]
To the Editor: We have read the report of the Simplicity HTN-1 investigators on the 2-year durability of blood pressure reduction induced by catheter-based renal sympathetic denervation with great excitement1 because it represents a promising approach for treatment of resistant hypertension.2 However, several concerns arise that require clarification.
Konstantinos, Petidis +2 more
openaire +2 more sources
The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Abdala, Ana P +7 more
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A rare case of renal thrombotic microangiopathy associated with Castleman’s disease [PDF]
BACKGROUND: Castleman’s disease (CD) is an uncommon, heterogeneous lympho-proliferative disorder leading to high circulating levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF).
Chen, Ying Maggie +3 more
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Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B +22 more
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Yanyan Li,1,* Qingqing Lou,2,* Song Wen,1 Mingyue Zhou,3 Dongxiang Xu,1 Chaoxun Wang,1 Xingdang Liu,2 Ligang Zhou1,4 1Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai, 201399, People’s Republic of China ...
Li Y +7 more
doaj
Evaluation of renal perfusion in hyperthyroid cats before and after radioiodine treatment [PDF]
Background: Hyperthyroidism and chronic kidney disease (CKD) are common in elderly cats. Consequently, both diseases often occur concurrently. Furthermore, renal function is affected by thyroid status. Because changes in renal perfusion play an important
Adams +34 more
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Alemtuzumab preconditioning with tacrolimus monotherapy - The impact of serial monitoring for donor-specific antibody [PDF]
BACKGROUND. Antibody preconditioning with tacrolimus monotherapy has allowed many renal allograft recipients to be maintained on spaced weaning. METHODS.
Adriana Zeevi +29 more
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