Results 191 to 200 of about 1,352,945 (362)

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee   +10 more
wiley   +1 more source

Role of atrial receptors in the control of sodium excretion [PDF]

open access: yes
Responses of an innervated and a contralateral chronically denervated kidney to mild positive pressure breathing are compared for saline volume expansions in chloralose anesthetized dogs.
Henry, J. P., Meehan, J. R.
core   +1 more source

Effects of Anethole on Renal Function of Swiss Mice. [PDF]

open access: yesPharmaceuticals (Basel)
Pinheiro-Lustosa R   +9 more
europepmc   +1 more source

RENAL FUNCTION DURING ANESTHESIA FOR CARDIOVASCULAR SURGERY [PDF]

open access: bronze, 1959
George C. Morris   +2 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Pharmacologic counter measures minimizing post-space flight orthostatic intolerance [PDF]

open access: yes
The effect of bed rest on drug disposition and physiological function was investigated as part of a project to determine the cardiovascular effects of space flight. One group of subjects was given doses of lidocane, penicillin-G, and ICG during a control
Harrison, D. C., Kates, R.
core   +1 more source

Renal Function Deterioration in Postoperative (Adjuvant) Chemotherapy for Colon Cancer-Real-Life Data. [PDF]

open access: yesCurr Oncol
Gładyś A   +9 more
europepmc   +1 more source

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