Results 271 to 280 of about 12,896,191 (434)
Predicting renal function using fundus photography: role of confounders. [PDF]
Park HW, Kim HR, Nam KY, Kim BJ, Kang T.
europepmc +1 more source
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li+11 more
wiley +1 more source
Sendotypes predict worsening renal function in chronic kidney disease patients. [PDF]
McLarnon T+11 more
europepmc +1 more source
piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
Circulating amyloid beta 1-40 peptide as an associate of renal function decline. [PDF]
Mavraganis G+15 more
europepmc +1 more source
NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao+13 more
wiley +1 more source
Three-month functional outcomes of acute ischemic stroke in patients with chronic renal function impairment. [PDF]
Hemmati D+4 more
europepmc +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source