Results 291 to 300 of about 12,283,849 (387)

Improved Orthogonality in Naphthalimide/Cyanine Dyad Boosts Superoxide Generation: a Tumor‐Targeted Type‐I Photosensitizer for Photodynamic Therapy of Tumor by Inducing Ferroptosis

Advanced Science, EarlyView.
A tumor‐targeted, renal‐metabolized, and less O2‐dependent Type‐I photosensitizer is presented for photodynamic therapy of tumors. The formation of an intramolecular sandwich‐like π–π assembly ensures its rigid orthogonal geometry, thereby improving the superoxide (O2•−)‐generating ability, promoting the intracellular formation of hydroxy radical (HO•),
Guangxiao Yao, Junfeng Miao, Yingying Huo, Wei Guo   +3 more
wiley   +1 more source

Osteoarthritis is a risk factor for renal function injury based on the National Health and Nutrition Examination Survey and Mendelian Randomized study. [PDF]

Sci Rep
Pang L, Wu K, Zhu Y, Wang Q, Zheng Z, Lv C, Bao Z.   +6 more
europepmc   +1 more source

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu, Wentao Zhang, Weiwei Liu, Zhao Ding, Ruijing Zhang, Yuefeng Han, Zihao Niu, Mengdie Zhang, Hui Li, Dapeng Li, Zixi Wang, Jie Peng, Yu Wu, Yanxun Han, Zihui Xie, Jing Wu, Liang Qin, Zhongdong Hu, Xu Chen, Yunlong Hu, Yehai Liu, Shiyin Ma, Xiaojun Zha   +22 more
wiley   +1 more source

Renal function outcomes in living kidney donors in a transplant center in Colombia. [PDF]

SAGE Open Med
Torres R, Reina M, Montero C, Tunjano A, Andrade D, Mancera V, Amaya M, Arias L, Castellanos L, Vanegas V.   +9 more
europepmc   +1 more source

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

Advanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen, Yifeng Zhang, Mirenuer Aikebaier, Yawei Du, Yan Liu, Qing Zha, Lan Zheng, Shuyao Shan, Yanping Wang, Jiawei Chen, Yiping Li, Ke Yang, Ying Yang, Wenguo Cui   +13 more
wiley   +1 more source

Renal function in diabetic retinopathy

Indian Journal of Ophthalmology, 1983
Khasgiwala S
doaj  

Hypertensive load predicts recovery of renal function for patients undergoing revascularisation for renal artery stenosis. [PDF]

Sci Rep
Edgar B, Pearson R, Jackson A, Stove C, Kasthuri R, Hussey K, Delles C, Geddes C, Mark P, Roditi G, McCallum L, Kingsmore DB.   +11 more
europepmc   +1 more source

Mechanisms and Therapeutic Strategies for Minority Cell‐Induced Paclitaxel Resistance and Tumor Progression Mediated by Mechanical Forces

Advanced Science, EarlyView.
This study provides new perspectives into the interactions between mechanical forces and cellular dynamics within the tumor microenvironment, particularly elucidating how minority Paclitaxel‐resistant cancer cells (MRCs) promote tumor progression and treatment resistance through mechanical forces and also providing effective treatment strategies for ...
Xueyan Feng, Di Zhang, Guoxun Wang, Liwei Lu, Feng Feng, Xiuyu Wang, Chanchan Yu, Yahong Chai, Jin Zhang, Wenchao Li, Jing Liu, Hongxia Sun, Li Yao   +12 more
wiley   +1 more source

Impact of Kalanchoe <i>(Kalanchoe daigremontiana</i>) Supplementation in Goat Maternal Diet on Hepatic and Renal Function and Reproductive Performance. [PDF]

Biology (Basel)
Vázquez-García JM, Ballesteros-Rodea G, Cuevas-Reyes V, Hernández-Arteaga LES, Peña-Avelino LY, López-Aguirre S, Sims R, Cavazos-Galindo JM, Rosales-Nieto CA.   +8 more
europepmc   +1 more source