Results 351 to 360 of about 12,896,191 (434)

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

Assessment of the renal function of patients with anorexia nervosa. [PDF]

Biopsychosoc Med
Miyahara H, Shigeyasu Y, Fujii C, Tanaka C, Hanzawa M, Sugihara A, Okada A, Tsukahara H.   +7 more
europepmc   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Renal function in diabetic retinopathy

Indian Journal of Ophthalmology, 1983
Khasgiwala S
doaj  

The impact of warm ischemia time on short-term renal function after partial nephrectomy: a systematic review and meta-analysis. [PDF]

BMC Urol
Li S, Guo Z, Li Y, Chan FL, Wang S, Gu C.   +5 more
europepmc   +1 more source

A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma

Advanced Science, EarlyView.
The current study has profiled the landscape of active enhancers in ccRCC and identified FABP5 as an oncogene. FABP5 is essential for the lipid droplet formation driven by HIFs and critical for H3K27ac and enhancer activity. The study has discovered the function of a feedback loop between epigenetics and lipid metabolism regulated by FABP5 in ccRCC ...
Zhou Ye, Qi‐Xin Hu, Ming‐Liang Wei, Ji‐Dong Chen, Jia Shi, Ning‐Rong Yang, Lu Jiang, Jian Chen, Zhi‐Yuan Chen, Wei‐Min Yu, Yu Xiao, Kai‐Yu Qian, Zilin Xu, Zhong Wang, Wen‐Lu Qi, Xin‐Yi Xiao, Yu‐Yu Duan, Yong Xiao, Lian‐Yun Li, Lin‐Gao Ju, Ming‐Kai Chen, Min Wu   +21 more
wiley   +1 more source

Comparative assessment of the effects of dotinurad and febuxostat on the renal function in chronic kidney disease patients with hyperuricemia. [PDF]

Sci Rep
Takata T, Taniguchi S, Mae Y, Kageyama K, Fujino Y, Iyama T, Hikita K, Sugihara T, Isomoto H.   +8 more
europepmc   +1 more source

Renal Function and the Role of the Renin-Angiotensin-Aldosterone System (RAAS) in Normal Pregnancy and Pre-Eclampsia. [PDF]

J Clin Med
Tsikouras P, Nikolettos K, Kotanidou S, Kritsotaki N, Oikonomou E, Bothou A, Andreou S, Nalmpanti T, Chalkia K, Spanakis V, Tsikouras N, Pagkaki C, Iatrakis G, Damaskos C, Garmpis N, Machairiotis N, Nikolettos N.   +16 more
europepmc   +1 more source

Investigation of renal function in patients with long COVID in the Amazon region: a cross-sectional study. [PDF]

BMC Infect Dis
Assis GMCC, Veiga IGD, Reis RNR, Menezes DC, Xavier SS, Chaves ECR, Sousa JR, Quaresma JAS, Falcão LFM, Lima PDL.   +9 more
europepmc   +1 more source

The impact of low-protein diet on residual renal function in dialysis patients: a systematic review and metaanalysis. [PDF]

BMC Nephrol
Xie J, Liu X, Ling Y, Ge S, Yao Y.
europepmc   +1 more source