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Carboplatin dosage: prospective evaluation of a simple formula based on renal function.
Journal of Clinical Oncology, 1989A dosage formula has been derived from a retrospective analysis of carboplatin pharmacokinetics in 18 patients with pretreatment glomerular filtration rates (GFR) in the range of 33 to 136 mL/min. Carboplatin plasma clearance was linearly related to GFR (
A. Calvert +9 more
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Angiotensin and renal function
International Urology and Nephrology, 1971The effects of angiotensin infused via the renal artery, and subsequently by the venous route, have been studied on the renal function in anaesthetized dogs. 1. Infusion of angiotensin into the renal artery in large doses (0.5 or 1.0 μg per min) produces a fall in the parameters of renal function to a certain level which even more massive doses ...
T. Bálint, Hilda Tost, Kövér G
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Renal function in hypertension
The American Journal of Medicine, 1988Hypertension certainly accelerates the age-related changes in renal structure and function, mainly in the glomerulus. Both sodium handling and the renin-angiotensin system are involved in the aging process. Among the available classes of antihypertensive agents, the eventual deterioration of renal function induced by angiotensin-converting enzyme ...
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Labetalol and renal function [PDF]
Irish Journal of Medical Science, 1981 Five patients with newly diagnosed hypertension treated with Labetalol in various dosage were assessed at fortnightly intervals after starting therapy to determine if any alteration in renal function had occurred. Before therapy, 2 patients had a normal glomerular filtration rate, one had a glomerular filtration rate of 71 mls/min and 2 had severe ...
A. J. S. Watson +2 more
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Monitoring Renal Function and Limitations of Renal Function Tests
Seminars in Nuclear Medicine, 2008Chronic kidney disease (CKD) is a world-wide public health problem, with adverse outcomes of kidney failure, cardiovascular disease, and premature death. The National Kidney Foundation, through its Kidney Disease Quality Outcome Initiative (K/DOQI) and other National institutions, recommend glomerular filtration rate (GFR) estimates for the definition,
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International Anesthesiology Clinics, 1984
The patient's history, physical examination, and routine urinalysis (including an expert assessment of the urinary sediment) are of paramount importance for the evaluation of a patient with possible renal dysfunction. The four tests most commonly used to establish the presence, extent, and the rate of progression of renal dysfunction are BUN, PCr, CCr,
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The patient's history, physical examination, and routine urinalysis (including an expert assessment of the urinary sediment) are of paramount importance for the evaluation of a patient with possible renal dysfunction. The four tests most commonly used to establish the presence, extent, and the rate of progression of renal dysfunction are BUN, PCr, CCr,
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The Journal of Pain, 2004
Opioids, both endogenous and exogenous, have a strong influence on the renal function through different mechanisms, producing changes in the renal excretion of water and sodium. Several studies have demonstrated that opioids influence renal function, according to the agonist profile used.
Sebastiano Mercadante, Edoardo Arcuri
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Opioids, both endogenous and exogenous, have a strong influence on the renal function through different mechanisms, producing changes in the renal excretion of water and sodium. Several studies have demonstrated that opioids influence renal function, according to the agonist profile used.
Sebastiano Mercadante, Edoardo Arcuri
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American Journal of Roentgenology, 2013 The objective of this article is to review and evaluate the various parameters used in determining renal status.The physiologic determination of renal status is the measured glomerular filtration rate (mGFR). Serum creatinine, blood urea nitrogen, cystatin C, and estimated GFR (eGFR), based on serum creatinine have failed to replace mGFR.
Eli Friedman, Joshua A. Becker
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Prostaglandins and Renal Function
2015Prostaglandins modulate the effects of vasoactive hormones by attenuating the renal actions of the renin-angiotensin system and contributing to and, perhaps, mediating some of those of the kallikrein-kinin system. A prostaglandin mechanism participates in the regulation of renin and erythropoietin release.
D A Terragno, J. C. McGiff, N A Terragno
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Toxicology Letters, 1989
Renal functional reserve represents the capacity of the kidney to increase its level of operation in response to certain demands. The reserve of glomerular filtration rate and of renal blood flow is discussed from the following points of view: evaluation, measurement, mechanisms involved and significance.
Claude Amiel +2 more
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Renal functional reserve represents the capacity of the kidney to increase its level of operation in response to certain demands. The reserve of glomerular filtration rate and of renal blood flow is discussed from the following points of view: evaluation, measurement, mechanisms involved and significance.
Claude Amiel +2 more
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