Inappropriate Doses of Intravenous Polymyxin B after Renal Adjustment Lead to Treatment Failure
Sub-therapeutic doses, shorter duration of therapy, female gender, bacteremia, and renal impairment were among independent predictors of polymyxin B treatment failure.
Bahiah Ismail +5 more
doaj +1 more source
Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco +6 more
core +1 more source
Tenofovir-associated renal toxicity in a cohort of HIV infected patients in Ghana
Objective Tenofovir disoproxil fumarate (TDF) is a nucleotide analogue recommended in international HIV treatment guidelines. Purpose of this study was to estimate the long term effects of TDF on renal profile in a cohort of HIV patients in Ghana.
Edmund T. Nartey +6 more
doaj +1 more source
Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B +22 more
core +8 more sources
Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? [PDF]
Aims: Changes in systolic blood pressure (SBP) during an admission for acute heart failure (AHF), especially those leading to hypotension, have been suggested to increase the risk for adverse outcomes.
Bourge, Robert C +17 more
core +5 more sources
Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment [PDF]
Introduction: This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care. Methods: A total of
Breen, Des +7 more
core +1 more source
Seasonal relapsing minimal change disease: a novel strategy for avoiding long-term immunosuppression. [PDF]
BACKGROUND: We describe the case of a young woman with seasonal allergic rhinitis who presented with signs of a lower respiratory tract infection, acute renal impairment and the nephrotic syndrome, demonstrated on biopsy to be due to minimal change ...
Cook, HT, Lawrence, C, Lightstone, L
core +2 more sources
Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D. +9 more
core +1 more source
Uncommon renal perihilar extramedullary haemopoiesis causing renal impairment [PDF]
A 74-year-old man with myelofibrosis on the background of myelodysplastic syndrome/myeloproliferative neoplasm was admitted for progressive decline of the renal function and progressive tiredness.
Konstantinos Stefanidis +3 more
openaire +2 more sources
Rolofylline, an adenosine A1−receptor antagonist, in acute heart failure [PDF]
Background: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved. We
Bloomfield, Daniel M +15 more
core +1 more source

