Results 151 to 160 of about 1,613,591 (292)

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie   +18 more
wiley   +1 more source

High-Sensitivity cardiac troponin I in the diagnosis of acute myocardial infarction: A study in patients with renal insufficiency. [PDF]

open access: yesAm Heart J Plus
Li Z   +11 more
europepmc   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency

open access: yes, 1996
G. Maschio   +8 more
semanticscholar   +1 more source

Association of serum bicarbonate with risk of renal and cardiovascular outcomes in CKD: a report from the Chronic Renal Insufficiency Cohort (CRIC) study.

open access: yesAmerican Journal of Kidney Diseases, 2013
M. Dobre   +15 more
semanticscholar   +1 more source

Strategic Timing of Gene Silencing: Cellular Kinetics‐Based Administration of siRNA for Optimized Photothermal Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Coordinating therapy with gene expression kinetics emerges as a key strategy for maximizing nanomedicine efficacy in aggressive cancers. A hybrid nanocarrier delivering HSP70‐targeting siRNA demonstrates this chronotherapeutic principle through systematic cellular profiling.
Tianliang Fang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy