Results 161 to 170 of about 1,613,591 (292)

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu, Benjie Xu, Rui Hu, Bo Yang, Peipei Shen, Yu Xu, Xiaojun Zhang, Danqi Qian, Gang Wu, Shengjun Ji, Yutian Zhao, Ke Gu   +11 more
wiley   +1 more source

Development and validation of a predictive model for in-hospital mortality in patients with coronary heart disease and renal insufficiency. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Li Y, Cai H, Zheng W, Wang M, Huang M, Wang L, Wang D, Zhao C, Hou W, Ding H, Wang Y, Zhu H.   +11 more
europepmc   +1 more source

A Multifunctional Molecular Probe for Multimodal Imaging‐Guided Potent Photothermal/Photodynamic Therapy of Endometriosis

Advanced Science, EarlyView.
The cRGD‐ILD molecular probe integrates clinically available components: a cRGD peptide (integrin αvβ3 targeting), ICG (for fluorescence/photoacoustic imaging and phototherapy), and Gd‐DTPA (MRI contrast). Utilizing small size and receptor targeting, it achieves selective lesion accumulation.
Qiyu Zhong, Shuguang Yang, Xiao Li, Zhuang Jin, Jianyu Ma, Zhouzhou Liao, Jinbo Li, Bo Li, Xintao Shuai, Shuqin Chen   +9 more
wiley   +1 more source

Renal insufficiency caused by <i>TMEM216</i> gene mutation: Case Report. [PDF]

Front Med (Lausanne)
Sun L, Xu M, Deng X, Liu X.
europepmc   +1 more source

Functional evaluation of penile hemodynamics [PDF]

, 1988
Bookstein, Brindley, Buvat, Ek, Jevtich, Juenemann, Jünemann, Karacan, Kockott, Lue, Lue, Newman, Porst, Sidi, Stief, van Arsdalen, Virag, Virag, Virag, Virag, Zorgniotti   +20 more
core   +1 more source

Effects of acute and chronic dosing of NSAIDs in patients with renal insufficiency

, 1986
Robert D. Toto, Shirley Anderson, Debbie Brown–Cartwright, Juha P. Kokko, D. Craig Brater   +4 more
openalex   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Endogenous digitalis–like factors in hypertension and chronic renal insufficiency

, 1986
Ralph A. Kelly, Donald S. O’Hara, William E. Mitch, Theodore I. Steinman, Robert C. Goldszer, Harold S. Solomon, Thomas W. Smith   +6 more
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Analysis of risk factors for poor prognosis in patients with renal insufficiency combined with <i>Enterobacteriaceae</i> bloodstream infection: a retrospective study. [PDF]

PeerJ
Wang Y, Zhao J.
europepmc   +1 more source