Results 171 to 180 of about 1,562,141 (341)

Association of serum bicarbonate with risk of renal and cardiovascular outcomes in CKD: a report from the Chronic Renal Insufficiency Cohort (CRIC) study.

open access: yesAmerican Journal of Kidney Diseases, 2013
M. Dobre   +15 more
semanticscholar   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du   +7 more
wiley   +1 more source

Thyroid hormone replacement therapy in dialysis/renal insufficiency patients. [PDF]

open access: yesFront Endocrinol (Lausanne)
Zhao X   +6 more
europepmc   +1 more source

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu   +7 more
wiley   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

open access: yesAdvanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen   +7 more
wiley   +1 more source

Evaluation of osteocalcin in serum of hemodialysis patients with renal insufficiency.

open access: bronze, 1986
K Torizumi   +7 more
openalex   +2 more sources

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong   +10 more
wiley   +1 more source

Functional evaluation of penile hemodynamics [PDF]

open access: yes, 1988
Bookstein   +20 more
core   +1 more source

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