Results 181 to 190 of about 1,634,332 (380)

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Diagnostic Significance of Dopamine Estimation Using Plasma and Urine in Patients with Adrenal and Renal Insufficiency, Renal Transplantation and Hypertension

, 1995
Manabu Yoshimura, Toshiaki Komori, Masato Nishimura, Yoshizumi Habuchi, Naohisa Fujita, Tadashi Nakanishi, Tadaki Yasumura, Hakuo Takahashi   +7 more
openalex   +2 more sources

Chronic Renal Insufficiency Cohort Study (CRIC): Overview and Summary of Selected Findings.

American Society of Nephrology. Clinical Journal, 2015
M. Denker, S. Boyle, A. Anderson, L. Appel, J. Chen, J. Fink, J. Flack, A. Go, Edward J. Horwitz, Chi-yuan Hsu, J. Kusek, J. Lash, S. Navaneethan, A. Ojo, Mahboob Rahman, S. Steigerwalt, R. Townsend, H. Feldman   +17 more
semanticscholar   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Use of sofosbuvir-based direct-acting antiviral therapy for hepatitis C viral infection in patients with severe renal insufficiency

Infectious Diseases, 2015
Gregory L. Hundemer, M. Sise, Jessica Wisocky, Nneka N. Ufere, L. Friedman, K. Corey, R. Chung   +6 more
semanticscholar   +1 more source

Macrophage‐Targeted Magnesium Ion‐Nourisher for NLRP3 Inflammasome Inhibition to Enhance Liver Inflammatory Disease Treatment

Advanced Science, EarlyView.
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang, Zhuo Yan, Sindhu Yalavarthi, Yusif Abdul‐Rashid, Kiki Parker, Kyle Nowlin, Ethan Li, Jordan Mack, Josephine Wei, Hunter Vu, Zhenquan Jia, Jianjun Wei, Jilong Wang, Kerui Wu   +13 more
wiley   +1 more source

The clinicopathological characteristics and safety analysis of renal needle biopsy in patients with severe renal insufficiency

Linchuang shenzangbing zazhi
ObjectiveTo analyze the clinicopathological characteristics and safety of renal needle biopsy in patients with severe renal insufficiency.MethodsPatients treated with percutaneous renal needle biopsy guided by B-ultrasound in the Department of Nephrology，
Zhang Ling-yan, Sun Jing, Sang Yong-yan, He Wei, Bian Qi   +4 more
doaj  

The effect of chronic usage of Renin-Angiotensin-Aldosterone System Blocking Agents on Incidence of Contrast-Induced Nephropathy in patients with Diabetes Mellitus and Renal Insufficiency. A Restropesctive Cohort Study

, 2019
Astika Widy Utomo, Dwi Aris Agung Nugrahaningsih, Iwan Dwiprahasto   +2 more
openalex   +2 more sources

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Lipidomic Signature of Progression of Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort

, 2016
Farsad Afshinnia, Thekkelnaycke M. Rajendiran, Alla Karnovsky, Tanu Soni, Xue Wang, Dawei Xie, Wei Yang, Tariq Shafi, Matthew R. Weir, Jiang He, Carolyn Brecklin, Eugene P. Rhee, Jeffrey R. Schelling, Akinlolu Ojo, Harold I. Feldman, George Michailidis, Subramaniam Pennathur, Lawrence J. Appel, Alan S. Go, John W. Kusek, James P. Lash, Raymond R. Townsend   +21 more
openalex   +1 more source