Results 1 to 10 of about 1,116,431 (255)

Renal nerve stimulation identifies renal innervation and optimizes the strategy for renal denervation in canine [PDF]

Journal of Translational Medicine, 2023
Background Renal denervation (RDN) was still performed without any intra-procedural method for nerve mapping. Whether renal nerve stimulation (RNS) is an efficient way to identify renal autonomic innervation and optimize the strategy for RDN remain to be
Hang Liu, Yidan Li, Hao Zhou, Weijie Chen, Yanping Xu, Huaan Du, Bo Zhang, Tianli Xia, Dan Li, Zhenhong Ou, Ruotian Tang, Qingsong Chen, Binyi Zhao, Yuehui Yin   +13 more
doaj   +2 more sources

Complex Hemodynamic Responses to Trans-Vascular Electrical Stimulation of the Renal Nerve in Anesthetized Pigs [PDF]

IEEE Open Journal of Engineering in Medicine and Biology
The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters.
Filippo Agnesi, Lucia Carlucci, Gia Burjanadze, Fabio Bernini, Khatia Gabisonia, John W Osborn, Silvestro Micera, Fabio A. Recchia   +7 more
doaj   +2 more sources

Renal nerve stimulation modulates renal blood flow in a frequency-dependent manner [PDF]

Bioelectronic Medicine
Background Chronic overactivity of the renal nerves is a key pathophysiological attribute of drug-resistant hypertension. Indeed, catheter-based renal denervation can lower blood pressure by severing the brain-kidney (efferent nerves) and kidney-brain ...
Dzifa Kwaku, Dusty Van Helden, Joan Dao, John Osborn, Matthew D. Johnson   +4 more
doaj   +2 more sources

The role of the renal afferent and efferent nerve fibres in heart failure [PDF]

Frontiers in Physiology, 2015
Renal nerves contain afferent, sensory and efferent, sympathetic nerve fibres. In heart failure (HF) there is an increase in renal sympathetic nerve activity, which can lead to renal vasoconstriction, increased renin release and sodium retention.
Lindsea C Booth, Clive N May, Song T Yao
doaj   +2 more sources

Prognostic Value of Sudomotor Small‐Fiber Function and Large Nerves for Accelerated Renal Decline in Type 2 Diabetes: A Real‐World Cohort Study [PDF]

Journal of Diabetes
Aims To evaluate the longitudinal prognostic value of small‐ and large‐fiber peripheral nerve assessments for accelerated renal decline in patients with Type 2 diabetes (T2D).
Qingyun Cai, Xiuqi Qiao, Sijia Fei, Yanxiang Luo, Lixin Guo, Qi Pan   +5 more
doaj   +2 more sources

Commentary: Renal Nerve Denervation [PDF]

JACC: Basic to Translational Science, 2016
Marcos Rothstein, MD
doaj   +2 more sources

Role of Renal Sympathetic Nerves in GLP‐1 (Glucagon‐Like Peptide‐1) Receptor Agonist Exendin‐4‐Mediated Diuresis and Natriuresis in Diet‐Induced Obese Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The gut‐derived hormone GLP‐1 (glucagon‐like peptide‐1) exerts beneficial effects against established risk factors for chronic kidney disease.
Xuefei Liu, Kaushik P. Patel, Hong Zheng
doaj   +1 more source

Renal Denervation by Noninvasive Stereotactic Radiotherapy Induces Persistent Reduction of Sympathetic Activity in a Hypertensive Swine Model

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We have previously reported the feasibility of noninvasive stereotactic body radiotherapy (SBRT) as a novel approach for renal denervation. Methods and Results Herein, from a translational point of view, we assessed the antihypertensive effect
Xingxing Cai, Yichen Shen, Yuli Yang, Wei Wang, Li Qian, Jing Cai, Runmin Chi, Shunxuan Yu, Keke Li, Zhixing Wei, Taizhong Chen, Yudong Fei, Yaqin Han, Xiu Chen, Ming Liu, Yifei Liu, Dengbin Wang, Mawei Jiang, Yi‐Gang Li   +18 more
doaj   +1 more source

Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. [PDF]

PLoS ONE, 2013
Nerve growth factor is a neurotrophin that promotes cell growth, differentiation, survival and death through two different receptors: TrkA(NTR) and p75(NTR).
Donatella Vizza, Anna Perri, Danilo Lofaro, Giuseppina Toteda, Simona Lupinacci, Francesca Leone, Paolo Gigliotti, Teresa Papalia, Renzo Bonofiglio   +8 more
doaj   +1 more source

GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation

Cardiovascular Diabetology, 2020
Background Glucagon-like peptide-1 (GLP-1) induces diuresis and natriuresis. Previously we have shown that GLP-1 activates afferent renal nerve to increase efferent renal sympathetic nerve activity that negates the diuresis and natriuresis as a negative ...
Kenichi Katsurada, Shyam S. Nandi, Hong Zheng, Xuefei Liu, Neeru M. Sharma, Kaushik P. Patel   +5 more
doaj   +1 more source