Results 51 to 60 of about 1,116,431 (255)

Role of leptin and insulin on renal sympathetic nerve activity in high fat fed rabbits

, 2022
Role of leptin and insulin on renal sympathetic nerve activity in high fat fed ...
Sandra L Burke (11215347), Benjie Barzel (13426074), Kyungjoon Lim (3597620), James Armitage (13059060), Geoffery A Head (13426080)   +4 more
core  

Renal Sympathetic Nerve-Derived Signaling in Acute and Chronic Kidney Diseases

, 2020
The kidney is innervated by afferent sensory and efferent sympathetic nerve fibers. Norepinephrine (NE) is the primary neurotransmitter for post-ganglionic sympathetic adrenergic nerves, and its signaling, regulated through adrenergic receptors (AR ...
Babu Padanilam, Hee-Seong Jang, Mi Noh, Jinu Kim   +3 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Shoulder posture and median nerve sliding [PDF]

, 2004
Background: Patients with upper limb pain often have a slumped sitting position and poorshoulder posture. Pain could be due to poor posture causing mechanical changes (stretch; localpressure) that in turn affect the function of major limb nerves (e.g ...
Lees, R, Julius, A, Lees Rebecca, Lynn Bruce, Lynn, B, Dilley, A, Julius Andrea, Dilley Andrew, Rebecca Lees, Andrew Dilley, Andrea Julius, Bruce Lynn   +11 more
core   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

A case of hypoglossal nerve palsy with evolving cranial nerve involvement in renal cell carcinoma: a case report

Journal of Medical Case Reports
Background Renal cell carcinoma is a rare pediatric solid tumor that typically presents with hematuria, abdominal mass, or flank pain. It is uncommon for renal cell carcinoma to manifest with headache and isolated extra-urogenital symptoms.
Shadi Shams, Abigail Broughton, Katrina Lambeth, Aditi Trivedi, Dehua Wang, Sun Choo, Katherine Dove   +6 more
doaj   +1 more source

Renal sympathetic nerve activity after catheter-based renal denervation

EJNMMI Research, 2018
Background Catheter-based renal sympathetic denervation (RDN) has been considered a potential treatment for therapy resistant hypertension (RHT). However, in a randomized placebo-controlled trial, RDN did not lead to a substantial blood pressure (BP ...
Linn C. Dobrowolski, Daan W. Eeftinck Schattenkerk, C. T. Paul Krediet, Peter M. Van Brussel, Liffert Vogt, Frederike J. Bemelman, Jim A. Reekers, Bert-Jan H. Van Den Born, Hein J. Verberne   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Renal sympathetic denervation:renal nerve stimulation [PDF]

, 2019
This thesis is a collection of research regarding high blood pressure and renal sympathetic denervation. High blood pressure is a silent killer and a major risk factor for cardiovascular disease.
de Jong, Mark Roland
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source