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Renal nerves in renal adaptation to dietary sodium restriction
To assess the physiologic importance of the renal nerves in the renal mechanisms for the maintenance of body sodium balance, renal adaptation to normal and low sodium diet was evaluated in conscious Sprague-Dawley male rats before and 8 days after recovery from bilateral surgical-pharmacological renal denervation.
G F, DiBona, L L, Sawin
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Heart, 2014
### Learning objectives Five years have passed since the first study on percutaneous renal denervation (RDN) to treat resistant hypertension was published.1 During its short life this technique has demonstrated its safety and efficacy in reducing blood pressure (BP), and also its appreciable indirect effects on cardiovascular remodelling and ...
Luca, Donazzan +3 more
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### Learning objectives Five years have passed since the first study on percutaneous renal denervation (RDN) to treat resistant hypertension was published.1 During its short life this technique has demonstrated its safety and efficacy in reducing blood pressure (BP), and also its appreciable indirect effects on cardiovascular remodelling and ...
Luca, Donazzan +3 more
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Intramedial Renal Arterial Nerves
Blood Vessels, 2008In this study, 5-hydroxydopamine was used to help differentiate adrenergic and nonadrenergic nerve terminals in canine renal arteries. There were both adrenergic and non-adrenergic varicosities in the adventitia near the outer surface of the media. The adrenergic varicosities had accumulated 5-hydroxydopamine, were more numerous than the nonadrenergic ...
D S, Knight +3 more
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Afferent Renal Nerves and Hypertension
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987Adenosine-sensitive nerve endings have been found in the renal pelvis which when stimulated increase sympathetic activity producing hypertension. When urinary adenosine concentration is lowered by intrarenal infusion of adenosine deaminase in one-kidney one-clip rats, peripheral sympathetic nervous system activity and arterial pressure decrease if the ...
R E, Katholi, W T, Woods
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Renal Nerves: Are They Essential?
New England Journal of Medicine, 1970The intrinsic innervation of the human kidney has been investigated for over 100 years. Until recently there has been no agreement concerning the distribution of these nerves. Studies using classic silver impregnation technics have shown, in addition to the nerve fibers of intrarenal blood vessels, what appeared to be nerve fibers innervating the ...
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The renal nerves in the newborn rat
Pediatric Nephrology, 1993Immunocytochemical methods were used to investigate the distribution of afferent [calcitonin gene-related peptide-(CGRP) immunoreactive and substance P-immunoreactive] nerves and efferent (neuropeptide Y-immunoreactive and dopamine beta-hydroxylase-immunoreactive) nerves in the kidneys of rats within the 1st day of life.
L, Barajas, L, Liu
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Regional responsiveness of renal perfusion to activation of the renal nerves
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2002We tested for regional differences in perfusion responses, within the renal medulla and cortex, to renal nerve stimulation in pentobarbital sodium-anesthetized rabbits. Laser-Doppler flux (LDF) was monitored at various depths below the cortical surface (1–15 mm).
Guild, Sarah-Jane +5 more
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Effects of Renal Nerves on Renal Hemodynamics
Nephron, 2008Renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (RBF), glomerular filtration rate (GFR), sodium excretion (UNaV), and intrarenal distribution of blood flow (microsphere method).
Murray A. Katz, Leroy Shear
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Journal of Human Hypertension, 2019
Renal denervation (RDN) is a well-known innovative therapy for hypertension. However, the effects of global RDN on blood pressure (BP) lowering are quite variable. Insufficient and futile denervation is considered a major factor contributing to the variable results.
Kunyue, Tan +10 more
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Renal denervation (RDN) is a well-known innovative therapy for hypertension. However, the effects of global RDN on blood pressure (BP) lowering are quite variable. Insufficient and futile denervation is considered a major factor contributing to the variable results.
Kunyue, Tan +10 more
openaire +2 more sources
Renal Nerves and Sodium Excretion
Annual Review of Physiology, 1979Claude Bernard (9) in 1859 was the first to report that unilateral section of the greater splanchnic nerve in the anesthetized dog resulted in the excre tion by the affected kidney of an increased volume of urine with decreased chloride concentration. These changes were reversible by electrical stimula tion of the distal cut end of the nerve. Similar
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