Results 21 to 30 of about 6,034 (173)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Diffuse cranial vault hyperostosis associated with long‐term antiepileptic therapy: Autopsy findings and differential diagnostic considerations

Journal of Forensic Sciences, EarlyView.
Abstract Diffuse cranial vault hyperostosis is an uncommon finding and may present a diagnostic challenge in clinical and forensic practice. We report the case of a 53‐year‐old woman with a long‐standing history of epilepsy treated with phenytoin and sodium valproate who collapsed at home suddenly and died despite resuscitative efforts.
Maria Piagkou, Athina Tousia, George Triantafyllou, Dimitrios Vlachodimitropoulos, Samer Al Besher, Panagiotis Manolarakis‐Papadopoulos, Alexandros Samolis, Stavroula Papadodima   +7 more
wiley   +1 more source

A Clinically Aligned Two‐Stage Machine Learning Framework for Predicting Hungry Bone Syndrome After Parathyroidectomy

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin, Yu‐Chieh Lin, Tzu‐Hsun Hung, Shen‐En Chou, Shun‐Yu Chi, Fong‐Fu Chou, Yi‐Ju Wu, Si‐Yuan Wu, Jenn‐Jier James Lien, Po‐Chih Kuo, Yi‐Chia Chan   +10 more
wiley   +1 more source

Risk factors predicting severe hypocalcemia after total parathyroidectomy without autotransplantation in patients with secondary hyperparathyroidism

Journal of International Medical Research, 2020
Objective This study was performed to investigate the risk factors for severe hypocalcemia (SH) after total parathyroidectomy without autotransplantation (TPTX) in patients with secondary hyperparathyroidism.
Jun Liu, Qinghua Huang, Meng Yang, Linping Huang, Ling Zhang   +4 more
doaj   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, Volume 30, Issue 3, Page 881-895, August 2026.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Investigation of renal osteodystrophy among hemodialysis patients referring to Towhid Hospital, Sanandaj, Iran

Chronic Diseases Journal, 2014
BACKGROUND: Renal osteodystrophy is a major complication among dialysis patients that can lead to muscle weakness, and bone pain and fractures by minor trauma.
Vahid Sedighi-Gourabi, Abdorrahim Afkhamzadeh, Bahram Nikkhu, Babak Rahimi-Rastgoo, Savgand Habibi, Gholam Moradinia   +5 more
doaj   +1 more source

An Unusual Cause of Diffuse Bone Pain in a Long‐Term Dialysis Patient: A Case Report of β2‐Microglobulin Amyloid Arthropathy

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Dialysis‐related amyloidosis (DRA) results from β2‐microglobulin accumulation in patients on long‐term hemodialysis, typically manifesting after 5–10 years. While well‐documented in developed countries, reports from sub‐Saharan Africa remain scarce.
Yannick Laurent Tchenadoyo Bayala, Mohamed Hanas Mama Sika, Marina Saley André Hamidou, Issa Ouedraogo, Rachidatou Kafando, Bakoubassé Aïssata Son, Wendyam Nadège Yameogo, Wendlassida Joëlle Stéphanie Zabsonré/Tiendrébéogo, Dieu‐Donné Ouedraogo   +8 more
wiley   +1 more source

Growth Hormone Therapy in Children with Chronic Renal Failure

Eurasian Journal of Medicine, 2019
Growth is impaired in a chronic renal failure. Anemia, acidosis, reduced intake of calories and protein, decreased synthesis of vitamin D and increased parathyroid hormone levels, hyperphosphatemia, renal osteodystrophy and changes in growth hormone ...
Atilla Cayir, Celalettin Kosan
doaj   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay, Alessia Brossa, Benedetta Bussolati   +2 more
wiley   +1 more source

The Mandibular Pattern in Renal Osteodystrophy

Turkish Journal of Nephrology, 2019
Renal osteodystrophy is one of the frequently seen problems in chronic hemodialysis patients who have a long life. The mandible is a rare location for renal osteodystrophy (ROD).
Gülperi ÇELİK, Ayşegül AKGÜN, Meltem SEZİŞ, Mehmet ÖZKAHYA   +3 more
doaj