Results 171 to 180 of about 3,596,940 (207)

A Germline BRCA2 Pathogenic Variant Identified by Multigene Panel Testing in Upper Tract Urothelial Carcinoma

open access: yesIJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Upper tract urothelial carcinoma (UTUC) is associated with Lynch syndrome; however, increasing evidence suggests broader genetic heterogeneity. Although multigene panel testing (MGPT) is increasingly adopted internationally, syndrome‐specific genetic testing (SSGT) remains predominant in Japan, potentially limiting detection of ...
Kazuna Matsuo   +6 more
wiley   +1 more source

Past, Present, and Future of Telerobotic Surgery in Urology: From Technological Breakthroughs to Global Adoption

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
The Development and Future of Remote Robots in Urology. ABSTRACT Ever since the “Lindbergh Operation” in 2001, the field of remote robotic surgery has transformed from theoretical study toward practical clinical integration on a global scale. Considering the millimeter‐level precision that is required in the field of urological oncology, remote ...
Cheng Yang   +6 more
wiley   +1 more source

Icariside II in Neurological Disorders: Mechanistic Insights Into Alzheimer's Disease, Cerebral Ischemia and Parkinson's Disease

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The graphical abstract represents the underlying neuroprotective potential of ICS II against Alzheimer's disease, Cerebral ischemia and Parkinson disease. ICS II downregulates ROS production, inflammation, mitochondrial dysfunction and apoptosis along with regulating their key signalling pathways.
Ashutosh Solanki   +4 more
wiley   +1 more source

Application of Serum CA125, HE4, ROMA, and CPH‐I in the Preoperative Differentiation of Ovarian Tumors: A Diagnostic Accuracy Study

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
This study evaluated the diagnostic performance of CA125, HE4, ROMA, and CPH‐I in 345 patients with histologically confirmed ovarian tumors. CPH‐I showed favorable diagnostic performance overall and was particularly valuable in premenopausal women, whereas ROMA‐based strategies demonstrated optimal performance in postmenopausal women.
Weiming Feng   +6 more
wiley   +1 more source

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 7, Page 1729-1735, September 2026.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

Complaints Involving Sonographers: What Three Decades of Cases From A Public New Zealand Database Can Teach Us

open access: yesJournal of Medical Radiation Sciences, Volume 73, Issue 3, Page 281-290, September 2026.
Health consumer complaints to the New Zealand Health and Disability Commissioner involving sonographers are rare, totalling 15 in the last 31 years and averaging 1.5 cases per year over the last decade. A large proportion of complaints involve an undetected finding, obstetric examination and private setting.
Martin Necas   +5 more
wiley   +1 more source

Best Practice Imaging in the Initial Investigation of Paediatric Blunt Abdominal Trauma: A Narrative Review

open access: yesJournal of Medical Radiation Sciences, Volume 73, Issue 3, Page 335-344, September 2026.
This narrative review synthesises current literature regarding paediatric blunt abdominal trauma imaging. It discusses the diagnostic performance of Focused Assessment with Sonography for Trauma, unenhanced and contrast‐enhanced ultrasound, as well as the impact of clinical decision rules for CT on clinical outcomes and radiation dose savings ...
Gemma Dongwon Lee   +5 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang   +13 more
wiley   +1 more source

Efficacy and Safety of Intraventricular Thiotepa in Combination With Methotrexate for Leptomeningeal Metastasis From Breast Cancer (NJMU‐BC04): A Single‐Arm Phase II Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Leptomeningeal metastasis (LM), an uncommon yet highly fatal condition, involves malignant tumor infiltration of the meninges resulting in progressive neurological deterioration and severe quality‐of‐life impairment. LM remains largely refractory to treatment and lacks standardized treatment consensus, with a low intracranial objective response rate ...
Wenbin Zhou   +10 more
wiley   +1 more source

Costello Syndrome Associated With Somatic Mosaicism of Rare p.Gly13Asp HRAS Variant: Expanding the Phenotypic Spectrum

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
We report a case of a 22‐year‐old woman with predominantly cutaneous involvement in whom whole‐exome sequencing from both blood‐ and hair‐derived DNA samples identified somatic mosaicism for the rare HRAS p.Gly13Asp variant. This case expands the phenotypic spectrum of Costello syndrome and underscores the importance of multitissue genomic analysis ...
Jovan Lalosevic   +6 more
wiley   +1 more source

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