Massive Ovarian Fibrothecoma Mimicking Advanced Ovarian Cancer in a High-Risk Patient: Diagnostic Challenges and Selective Use of Preoperative Biopsy. [PDF]
Xu W, Yao J, Li J, Zhang Y.
europepmc +1 more source
The graphical abstract represents the underlying neuroprotective potential of ICS II against Alzheimer's disease, Cerebral ischemia and Parkinson disease. ICS II downregulates ROS production, inflammation, mitochondrial dysfunction and apoptosis along with regulating their key signalling pathways.
Ashutosh Solanki +4 more
wiley +1 more source
Invasive Urothelial Carcinoma Presenting With Combined Obstructive Uropathy and Ischemic Small- and Large-Bowel Obstruction. [PDF]
Gabrielyan G +4 more
europepmc +1 more source
This study evaluated the diagnostic performance of CA125, HE4, ROMA, and CPH‐I in 345 patients with histologically confirmed ovarian tumors. CPH‐I showed favorable diagnostic performance overall and was particularly valuable in premenopausal women, whereas ROMA‐based strategies demonstrated optimal performance in postmenopausal women.
Weiming Feng +6 more
wiley +1 more source
Case Report: A rare case of fumarate hydratase (FH)-deficient uterine leiomyoma in a 39-year-old woman: a sentinel finding prompting hereditary cancer syndrome evaluation. [PDF]
Li N, He L.
europepmc +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
PD-1/PD-L1 inhibitor-related cystitis: clinical features, diagnostic exclusion, and outcomes in one definite and seven probable cases with an updated literature review. [PDF]
Ding W +7 more
europepmc +1 more source
Leptomeningeal metastasis (LM), an uncommon yet highly fatal condition, involves malignant tumor infiltration of the meninges resulting in progressive neurological deterioration and severe quality‐of‐life impairment. LM remains largely refractory to treatment and lacks standardized treatment consensus, with a low intracranial objective response rate ...
Wenbin Zhou +10 more
wiley +1 more source
Durable response to pembrolizumab plus axitinib in platinum-resistant ovarian clear cell carcinoma: A case report. [PDF]
Patel NS +4 more
europepmc +1 more source
We report a case of a 22‐year‐old woman with predominantly cutaneous involvement in whom whole‐exome sequencing from both blood‐ and hair‐derived DNA samples identified somatic mosaicism for the rare HRAS p.Gly13Asp variant. This case expands the phenotypic spectrum of Costello syndrome and underscores the importance of multitissue genomic analysis ...
Jovan Lalosevic +6 more
wiley +1 more source

