Results 261 to 270 of about 1,372,792 (350)

Organ‐specific low‐dose assessment in pediatric radiotherapy using nanodot OSL and NTCP modeling: Application to medulloblastoma

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background In pediatric radiotherapy, controlling low‐dose exposure is a major challenge, particularly in the treatment of medulloblastoma, where the long life expectancy of young patients makes optimization of radioprotection crucial. Purpose This study provides a comprehensive and quantitative assessment of low‐dose exposure to normal ...
Meriem Tantaoui   +6 more
wiley   +1 more source

Extracellular‐Matrix‐Based Materials from Decellularized Tissue: Opportunities, Challenges, and Future Directions in Regenerative Medicine

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
Extracellular matrix‐based materials derived from decellularized tissue (dECM) harness the tissue's native bioactivity to guide repair and regeneration across diverse clinical applications. This perspective highlights clinical uses of dECM biomaterials and advances in fabrication methods such as electrospinning and 3D printing.
Madeline Laude   +4 more
wiley   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 15-24, January 2026.
This prospective randomized trial demonstrated that a 4‐day regimen of sulbactam/ampicillin significantly reduced the incidence of perineal wound infection (PWI) following abdominoperineal resection compared to a 1‐day cefmetazole regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Akitoshi Nankaku   +12 more
wiley   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

open access: yesAmerican Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi   +11 more
wiley   +1 more source

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