Results 91 to 100 of about 457,723 (363)

Long-term outcome in ICU patients with acute kidney injury treated with renal replacement therapy: a prospective cohort study

open access: yesCritical Care, 2016
BackgroundIn intensive care unit (ICU) patients, acute kidney injury treated with renal replacement therapy (AKI-RRT) is associated with adverse outcomes.
W. De Corte   +8 more
semanticscholar   +1 more source

Renal Replacement Therapy in Icu's

open access: yesApollo Medicine, 2005
Acute Renal Failure complicates the course of many disease in the setting of sepsis. It has been known to account for the mortality in 56% of ICU patients. Hemodynamically unstable patients of acute renal failure in ICU have always proved a challenge to dialysis units. During the last decade, continuous renal replacement therapy (CRRT) has emerged as a
Vishai Saxena, Ashok Sarin
openaire   +2 more sources

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Symptom burden in patients with chronic kidney disease not requiring renal replacement therapy

open access: yesClinical Kidney Journal, 2017
Background Although evidence shows that patients with end stage renal disease (ESRD) experience a high symptom burden which impacts on quality of life (QoL), less is known about patients with earlier stages of chronic kidney disease (CKD).
S. A. Brown   +7 more
semanticscholar   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications

open access: yesCritical Care, 2016
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
G. Villa   +69 more
semanticscholar   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Exploring challenges and considerations while providing hemodialysis to pediatric, elderly, and pregnant cases: A narrative review of globally published literature

open access: yesClinical Epidemiology and Global Health
Background: Hemodialysis patients have unique physiological characteristics that necessitate specialized care during the treatment. As the prevalence of kidney disease continues to rise, the importance of addressing the unique needs of these patient ...
Megha Nagaraj Nayak, Veena Natti Krishna
doaj  

Renal replacement therapy in Europe: a summary of the 2013 ERA-EDTA Registry Annual Report with a focus on diabetes mellitus

open access: yesClinical Kidney Journal, 2016
Background This article provides a summary of the 2013 European Renal Association–European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at http://www.era-edta-reg.org), with a focus on patients with diabetes mellitus ...
A. Kramer   +53 more
semanticscholar   +1 more source

Ethnicity and Renal Replacement Therapy [PDF]

open access: yesBlood Purification, 2010
There are significant ethnic variations in the incidence of kidney disease. White European populations appear to be uniquely protected compared to increased incidences of end-stage renal disease in indigenous and migrant ethnic minority populations. This increase is partly explained by a high prevalence of diabetic nephropathy, but there is also an ...
openaire   +4 more sources

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