Results 91 to 100 of about 618,690 (430)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Use orotic acid in the treatment of pathological conditions associated with hyperuricemia

open access: yesPočki, 2014
Hyperuricemia - a condition characterized by elevated relative to normal ranges, levels of uric acid in the blood. Among the diseases caused by hyperuricemia, most noteworthy are gout, urate nephropathy, and urolithiasis.
D.D. Ivanov, Ya.A. Dombrovskyi
doaj   +1 more source

Evaluation of modifiable risk factors for peritoneal dialysis-related peritonitis: a single-center retrospective cohort study

open access: yesRenal Replacement Therapy, 2021
Background Peritoneal dialysis (PD)-related peritonitis risk factors can be categorized as modifiable and uncorrectable. We aimed to identify modifiable risk factors for PD-related peritonitis in our facility to prevent PD-related peritonitis and ...
Shigeki Kojima   +5 more
doaj   +1 more source

Highly Efficient Stepped Wedge Designs for Clusters of Unequal Size [PDF]

open access: yes, 2018
The Stepped Wedge Design (SWD) is a form of cluster randomized trial, usually comparing two treatments, which is divided into time periods and sequences, with clusters allocated to sequences. Typically all sequences start with the standard treatment and end with the new treatment, with the change happening at different times in the different sequences.
arxiv   +1 more source

Data-Driven Modeling and Control of Complex Dynamical Systems Arising in Renal Anemia Therapy [PDF]

open access: yesarXiv, 2021
This project is based on a mathematical model of erythropoiesis for anemia, which consists of five hyperbolic population equations describing the production of red blood cells under treatment with epoetin-alfa (EPO). Extended dynamic mode decomposition (EDMD) is utilized to approximate the non-linear dynamical systems by linear ones.
arxiv  

Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose/objective We propose a novel lattice deployment for spatially fractionated radiotherapy (SFRT) treatments. In this approach, a larger diameter high‐dose sphere is centrally placed in the bulky tumor mass and surrounded by smaller diameter high‐dose spheres.
Joshua Misa   +2 more
wiley   +1 more source

Evaluation of an automated choroid segmentation algorithm in a longitudinal kidney donor and recipient cohort [PDF]

open access: yesarXiv, 2023
Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring renal transplantation over up to 1 year post-transplant.
arxiv  

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita   +7 more
wiley   +1 more source

Hyperkalemia management in children with chronic kidney disease

open access: yesPočki, 2019
Background. Hyperkalemia is the most common electrolyte disorder in patients with kidney disease, especially with chronic kidney disease (CKD), diabetes mellitus, heart failure, or in those who are treated with renin-angiotensin-aldosterone system ...
S.V. Kushnirenko
doaj   +1 more source

The changing trends and outcomes in renal replacement therapy: data from the ERA-EDTA Registry.

open access: yesNephrology, Dialysis and Transplantation, 2016
BACKGROUND This study examines the time trends in incidence, prevalence, patient and kidney allograft survival and causes of death (COD) in patients receiving renal replacement therapy (RRT) in Europe.
M. Pippias   +20 more
semanticscholar   +1 more source

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