Results 131 to 140 of about 486,423 (351)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Successful autologous blood pleurodesis in two maintenance hemodialysis patients with idiopathic refractory pleural effusion: case reports and literature review

Renal Replacement Therapy
Background Refractory pleural effusion occasionally occurs in patients undergoing maintenance hemodialysis and is associated with a poor prognosis. We recently encountered idiopathic refractory pleural effusion in two patients undergoing maintenance ...
Ryoichi Miyazaki, Kyoko Miyagi, Tatsuhito Miyanaga, Kazuhiko Igarashi, Mitsuo Awaji   +4 more
doaj   +1 more source

A high aminoglycoside regimen associated with renal replacement therapy for the treatment of multi-drug resistant pathogens [PDF]

, 2015
Alexandre Brasseur, Maya Hites, Sandrine Roisin, Frédéric Cotton, Jean‐Louis Vincent, Daniel De Backer, Frédéric Jacobs, FS Taccone   +7 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Inhibition of repaglinide metabolism by letermovir prolonged severe hypoglycemia in a kidney transplant recipient: A case report and literature review

Renal Replacement Therapy
Background The prevention of cytomegalovirus (CMV) infection after kidney transplantation (KTx) is important. Letermovir (LTV), a drug used for CMV prophylaxis, has various drug–drug interactions.
Takashi Tsujimoto, Hiroki Kanou, Asuka Yamamoto, Hajime Sasaki, Tatsu Tanabe   +4 more
doaj   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Ectopic parathyroid hormone-producing cervical cancer requiring hemodialysis owing to acute hypercalcemia: a case report

Renal Replacement Therapy
Background Parathyroid hormone-related protein (PTHrP) is often the underlying cause of malignancies complicated by hypercalcemia. However, in rare instances, ectopic production of parathyroid hormone (PTH) by tumors can be responsible, with ...
Yusuke Ushio, Yosuke Iwatani, Mayuko Suyama, Ayano Tanaka, Mihoko Mizutani, Momoko Seki, Yuka Shimizu, Koichiro Shiogai, Nagisa Ando, Nozomi Sato, Kouta Higashi, Masahide Tazawa, Kana Nomura, Haruka Kato, Anna Nakai, Hitoko Sumori, Shiho Makabe, Shizuka Kobayashi, Yuki Kawaguchi, Shun Manabe, Hiroshi Kataoka, Naoko Ito, Sekiko Taneda, Tomoko Yamamoto, Kosaku Nitta, Junichi Hoshino   +25 more
doaj   +1 more source

Prevention of unplanned interruption in critically ill continuous renal replacement therapy patients:a best practice implementation project [PDF]

Xianfeng Liu, Shanshan Lv, Xiuquan Wang, Hui Fang, Guixia Li, Yingying Cheng, Haotian Zhang, Jing Zheng   +7 more
openalex   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source