Results 231 to 240 of about 171,022 (301)

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

A Comparative Nonrandomised Observational Study of Different Modalities of Renal Replacement Therapy (Continuous Renal Replacement Therapy vs. Sustained Low Efficiency Dialysis) With Acute Kidney Injury in an Intensive Care Unit Setup: A Pilot Study. [PDF]

Cureus
Dash CS, Harbada R, Deshpande RV, Khan Pathan A.   +3 more
europepmc   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

A Case of Pediatric Yersinia pseudotuberculosis Infection Complicated by Acute Kidney Injury Successfully Treated With Prednisolone Without Renal Replacement Therapy. [PDF]

Cureus
Ohnishi T, Sato S, Uejima Y, Miyata I, Suganuma E.   +4 more
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Development of a feasible and portable electronic flag for near-real-time identification of renal replacement therapy in the Veterans Health Administration. [PDF]

Antimicrob Steward Healthc Epidemiol
Golenbock SW, Basnet D, Mull HJ, Lamkin R, Harvey K, Shin M, Strymish JM, Leatherman S, Ferguson R, Branch-Elliman W.   +9 more
europepmc   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

Continuous renal replacement therapy in a neonate with methylmalonic acidemia and severe hyperammonemia: A case report. [PDF]

Medicine (Baltimore)
Lin B, Huang Y, Yu Y, Xiong X, Yang C.
europepmc   +1 more source

Clinical Profile and Outcomes of Hospitalized Coronavirus Disease-2019 Patients Requiring Renal Replacement Therapy at a Tertiary Care Center

Ashish Chauhan, Ram Singh, Dheeraj Sharma, Rajeev Sandal, Balbir Singh Verma, Naresh Chauhan, Sanjay Vikrant, Samriti Gupta, Asheesh Kumar   +8 more
openalex   +1 more source

Empowering Flexible Electronics with Piezoelectric Nanogenerators: Breakthroughs from Energy Harvesting to Intelligent Sensing

Advanced Science, EarlyView.
This review systematically summarizes recent advances in self‐powered flexible sensing and energy storage systems based on piezoelectric nanogenerators (PENGs). It highlights their fundamental mechanisms, structural designs, and applications in health monitoring, e‐skin, and tactile sensing. The integration of PENGs with supercapacitors or batteries is
Wu‐Lin Xin, He‐Qing Cai, Xi Cui, Lu Han, Kou Zhang, Xin‐Yu Xue, Yi‐Fei Song, Juan Liu, Zhou Li   +8 more
wiley   +1 more source