Results 231 to 240 of about 486,423 (351)

Renal Replacement Therapy in the Critically Ill Child*

open access: yesPediatric Critical Care Medicine, 2018
C. Westrope   +4 more
semanticscholar   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao   +11 more
wiley   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

WCN24-772 COMPARATIVE ANALYSIS OF THE COVID-19 COURSE IN THE KIDNEY TRANSPLANT RECIPIENTS DURING DIFFERENT EPIDEMIOLOGICAL PERIODS

open access: yesKidney International Reports
Kirill Komissarov   +4 more
doaj   +1 more source

Critically Ill Patients with COVID-19 Pneumonia Requiring Continuous Renal Replacement Therapy with oXiris<sup>®</sup> Membrane in a Third-Level Hospital in Northeast Mexico [PDF]

open access: bronze
Paola Borbolla-Flores   +6 more
openalex   +1 more source

Renal Replacement Therapy and Conservative Management

open access: yesFamily Medicine, 2019
С. О. Шурпяк
semanticscholar   +1 more source

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