Results 271 to 280 of about 457,723 (363)

Influence of the arterial elastic component on the response to balloon angioplasty in femoral arteries of a healthy porcine model

Animal Models and Experimental Medicine, EarlyView.
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García, Marina Gil Bernabé, Claudia Pérez‐Martínez, Laura Mola Solà, Luis Duocastella Codina, María Molina Crisol, Alex Gómez Castel, Armando Pérez de Prado   +7 more
wiley   +1 more source

Thrombocytopenia in Children and Young Adults Undergoing Continuous Renal Replacement Therapy: A WE-ROCK Study.

Blood Purif
Basalely A, Gist KM, Stanski NL, Fuhrman DY, Seo J, Ollberding NJ, Strong A, Damian M, Morgan C, Reynaud S, Muff-Luett M, Deep A, Serpe C, Krallman KA, Menon S, WE-ROCK Investigators.   +15 more
europepmc   +1 more source

Hyperlactatemia in critically ill patients with acute kidney injury treated with renal replacement therapy in the intensive care unit. [PDF]

BMC Nephrol
Ekart R, Kobal B, Korošec T, Jakopin E, Svenšek F, Piko N, Bevc S, Hojs R.   +7 more
europepmc   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Strategies for optimization of hypoglycemia rat models

Animal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher, Eason Kong Qi Zheng, Rayneshia Elaura Raymond, Ye Zhen Jie, Christina Gertrude Yap   +4 more
wiley   +1 more source

Trajectories of fluid management after the initiation of renal replacement therapy in critically ill patients: a secondary analysis of the STARRT-AKI trial. [PDF]

Crit Care
Beaubien-Souligny W, Gamarian E, Côté JM, Neyra JA, Baroz F, Adhikari NKJ, Thorpe K, Bagshaw SM, Wald R.   +8 more
europepmc   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Use of hematological indices in severe septic acute kidney injury to predict hospital mortality and need for renal replacement therapy at discharge. [PDF]

SAGE Open Med
Vargas Ángel DC, Chaparro CA, Muñoz OM, Contreras-Villamizar K, González CA, Martín DA, Galindo LV.   +6 more
europepmc   +1 more source

Sheep femoral artery occlusion is well tolerated and does not result in ischemia

Animal Models and Experimental Medicine, EarlyView.
Left femoral artery occlusion (yellow arrows) can be seen shortly after the lateral femoral circumflex artery origin, with distal arterial reconstitution. Sheep with femoral artery occlusion showed no change in pain scores nor mobility, thus making them an appropriate model for novel small diameter femoral artery graft studies. Abstract Objective Sheep
Timothy Shiraev, Ziyu Wang, Lakshay Seth, Lisa Partel, Innes K. Wise, Hugh Paterson, John O'Sullivan, Sean Lal, Anthony S. Weiss, Paul Bannon, Robert D. Hume   +10 more
wiley   +1 more source

Limiting the gamble: Risk and predictability for renal replacement therapy in patients receiving mechanical circulatory support★. [PDF]

J Extra Corpor Technol
Gore K, Linder D, Martinez Duque JJ, Wang J, Wester B, Otero T, Yockelson S, Ruiz AA, Nossaman BD.   +8 more
europepmc   +1 more source