Results 81 to 90 of about 618,690 (430)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Delaying treatment for peritonitis could be related to longer hospitalization in patients on peritoneal dialysis

Renal Replacement Therapy
Background When peritoneal dialysis (PD)-related peritonitis occurs in PD patients, diagnostic and therapeutic approaches should be started as soon as possible.
Yusaku Koshitori, Nami Takai, Yoshihito Isomura, Tetsuaki Hiramatsu, Yasuhiro Suzuki, Hangsoo Kim, Sosuke Fukui, Masashi Mizuno   +7 more
doaj   +1 more source

SPossibilities of 4-Component Therapy in Renal Protection: UNIKUM Trial Results

Počki, 2012
There are given the results of first in Ukraine experience of 4-component therapy (angiotensin II receptor blockers, β-blocker, acetylsalicylic acid, statin) — multimodal strategy under randomized study in patients with chronic renal disease.
D.D. Ivanov
doaj   +1 more source

Patient-reported symptoms during dialysis: the effect of pre-dialysis extracellular water and change in extracellular water post-dialysis

Renal Replacement Therapy, 2021
Background Quality of life for haemodialysis (HD) patients may be affected by symptoms during dialysis treatments, and patient groups have highlighted the need to improve post-dialysis fatigue and dialysis-related symptoms.
Suree Yoowannakul, Surachet Vongsanim, Kamonwan Tangvoraphonkchai, Ahmed Mohamed, Andrew Davenport   +4 more
doaj   +1 more source

Time-dependent Clearance of Cyclosporine in Adult Renal Transplant Recipients: A Population Pharmacokinetic Perspective [PDF]

arXiv, 2021
Aim The pharmacokinetic (PK) properties of cyclosporine (CsA) in renal transplant recipients are patient- and time-dependent. Knowledge of this time-related variability is necessary to maintain or achieve CsA target exposure. Here, we aimed to identify factors explaining variabilities in CsA PK properties and characterise time-dependent clearance (CL/F)
arxiv  

Full modelling of high-intensity focused ultrasound and thermal heating in the kidney using realistic patient models [PDF]

IEEE Transactions on Biomedical Engineering 65.11 (2018): 2660-2670, 2017
Objective: High-intensity focused ultrasound (HIFU) therapy can be used for non-invasive treatment of kidney (renal) cancer, but the clinical outcomes have been variable. In this study, the efficacy of renal HIFU therapy was studied using nonlinear acoustic and thermal simulations in three patients. Methods: The acoustic simulations were conducted with
arxiv   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Nifuratel Application in Therapy of Urinary Tract Infections

Počki, 2014
The article examines the treatment of urinary tract infections, in particular attention was paid to antibiotic therapy. It is emphasized that the results of many studies and practical experience enable to consider group of nitrofurans, including ...
Ya.A. Dombrovskyi, D.D. Ivanov
doaj   +1 more source

Indications of initiation renal replacement therapy among patients with chronic renal disease [PDF]

, 2016
Introduction: Chronic renal failure (CRF) is a major cause of morbidity and mortality and renal replacement dialysis is necessary for the preservation of life, despite the fact that it is characterized by multiple restrictions and complications.Aim: The ...
Florou, Alexandra, Margari, Nikoleta, Theofanidis, Dimitrios   +2 more
core   +1 more source

Clinical review: Timing of renal replacement therapy [PDF]

, 2011
Acute kidney injury is common in intensive care patients and continuous renal replacement therapy is the preferred treatment for this in most centres. Although these techniques have been adopted internationally, there remains significant variation with ...
Forni, Lui G, Joannidis, Michael
core   +2 more sources