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Impact of renal denervation on circadian variations of blood pressure and clock gene expression in spontaneously hypertensive rats. [PDF]
Front Cardiovasc MedYang GY, Chen SK, Luo SQ, Su JZ, Cai WQ.
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Renal Sympathetic Denervation for the Treatment of Refractory Hypertension
Annual Review of Medicine, 2014Resistant hypertension poses significant health concerns. There are strong demands for new and safe therapies to control resistant hypertension while addressing its common causes, specifically poor compliance to lifelong polypharmacy, lifestyle modifications, and physician inertia.
Antony Walton
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Renal Sympathetic Denervation: A Comprehensive Review
Current Problems in Cardiology, 2021In 2017, the American College of Cardiology and American Heart Association released its updated blood pressure guidelines, redefining hypertension to be any systolic blood pressure ≥130 mm Hg or diastolic blood pressure ≥80 mm Hg. Among United States adults, these new parameters increased the prevalence of hypertension from 72.2 million (31.9%) to 103 ...
Oluwaseun A, Akinseye +5 more
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Renal sympathetic denervation: Recalculating…
Catheterization and Cardiovascular Interventions, 2016Key Points Renal sympathetic denervation may serve as a treatment alternative in patients with resistant systemic arterial hypertension. Ablation at the proximal and distal renal artery branches with an irrigated catheter did not lead to better blood pressure reduction than proximal ablation alone.
Jorge A, Belardi, Mariano, Albertal
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Renal sympathetic denervation in hypertension
Current Opinion in Nephrology and Hypertension, 2011Despite the abundance of antihypertensive drugs, resistant hypertension remains a major clinical problem. Recent technological advances render interventional management of resistant hypertension one of the hottest topics in the hypertension field. The aim of this review is to present the pathophysiologic background and the mechanisms mediating blood ...
Michael, Doumas +2 more
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Renal Sympathetic Denervation and Renal Physiology
Current Clinical Pharmacology, 2013The sympathetic nervous system has a profound effect on the kidney's ability to regulate blood pressure and, vice versa, the kidney has an important effect on the overall sympathetic tone. As a result, renal sympathetic nerves are crucial for initiation and the maintenance of systemic hypertension.
Rigas G, Kalaitzidis +2 more
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Renal Sympathetic Denervation for Treatment of Hypertension
Current Treatment Options in Cardiovascular Medicine, 2012OPINION STATEMENT: Sympathetic nervous system activation of the heart, kidney and peripheral vasculature increases cardiac output, fluid retention and vascular resistance and plays an important role in acute and chronic BP elevation. Renal sympathetic denervation via a percutaneous radiofrequency catheter based approach is a safe and effective ...
Pimenta, Eduardo, Oparil, Suzanne
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Renal Sympathetic Denervation in Rats
2015Experimental renal sympathetic denervation is a well-established technique. Classically, renal sympathetic denervation is achieved by dorsal rhizotomy. While more recently, direct renal sympathetic denervation is typically applied by stripping all visible renal nerve bundles followed by painting with a solution of 10 % phenol in ethanol to remove the ...
Masahiro, Eriguchi, Kazuhiko, Tsuruya
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Renal Sympathetic Denervation and Systemic Hypertension
The American Journal of Cardiology, 2010Hypertension represents a major health problem, with an appalling annual toll. Despite the plethora of antihypertensive drugs, hypertension remains resistant in a considerable number of patients, thus creating the need for alternative strategies, including interventional approaches.
Michael, Doumas +2 more
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