Results 91 to 100 of about 190,539 (312)
Background: Benign prostatic hyperplasia affects about 210 million males as of 2010 (6% of the population). BPH is the most common disease of men above 50 years of age. BPH is a major cause of morbidity in the ageing men.
Ram Sagar Shah+6 more
doaj +1 more source
Tacrolimus in Renal Transplantation [PDF]
Tacrolimus (Prograf-FK506) has been used since 1989 as a primary immunosuppressive agent in adult and pediatric renal transplant recipients at our institution.1,2 This report will summarize our experience with it over the past six years and will demonstrate its overall efficacy and superiority.
Shapiro, R+15 more
openaire +3 more sources
A dual‐response DNA origami platform is developed for the early diagnosis and therapeutic intervention of sepsis‐associated acute kidney injury. Abstract Current diagnostics for sepsis‐associated acute kidney injury (SA‐AKI) detect kidney damage only at advanced stages, limiting opportunities for timely intervention. A DNA origami‐based nanoplatform is
Yingying Zhao+8 more
wiley +1 more source
Abstract Objectives To assess the correlation between the aortic valve annular plane (AVAP) obtained by preprocedural computed tomography (CT) with on‐table three‐dimensional rotational angiography (3DRA), in patients undergoing transcatheter aortic valve replacement (TAVR).
Richard Tanner+9 more
wiley +1 more source
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang+6 more
wiley +1 more source
Gitelman Syndrome: a Сlinical and Molecular Overview
Gitelman syndrome (OMIM #263800) is an autosomal recessive renal tubular disorder due to loss of function mutations of SLC12A3 gene, encoding the thiazide-inhibitable, electroneutral Na+-Cl– cotransporter (NCC) of the distal convoluted tubule.
Maria Luisa Querques+3 more
doaj +1 more source
K-Nearest Neighbour algorithm coupled with logistic regression in medical case-based reasoning systems. Application to prediction of access to the renal transplant waiting list in Brittany [PDF]
Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output).
arxiv
Enhancing kidney quality assessment: Power Doppler during normothermic machine perfusion [PDF]
Objectives: Marginal donor kidneys are increasingly used for transplantation to overcome organ shortage. This study aims to investigate the additional value of Power Doppler (PD) imaging in kidney quality assessment during normothermic machine perfusion (NMP).
arxiv +1 more source
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang+9 more
wiley +1 more source
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang+4 more
wiley +1 more source