Results 111 to 120 of about 190,539 (312)
Aggregate, EarlyView.The study reveals that optimizing various parameters of sonodynamic therapy (SDT), including the functional characteristics of sonosensitizers and the optimization of acoustic parameters, can significantly enhance SDT therapeutic efficacy. When combined with chemotherapy, this approach effectively overcomes tumor resistance and induces antitumor immune
Zhuoran Gong +6 more
wiley +1 more source
Predicting progression of aortic stenosis by measuring serum calcification propensity
Clinical Cardiology, Volume 45, Issue 12, Page 1297-1302, December 2022., 2022 Abstract Background The aim of this prospective, double‐blinded study in patients with aortic sclerosis was to determine whether a new calcification propensity measure in the serum could predict disease progression. Methods We included 129 consecutive patients with aortic sclerosis as assessed during a routine clinical echocardiographic exam. Clinical,
Reto Kurmann +4 more
wiley +1 more source
A new pharmacological preconditioning-based target: from drosophila to kidney transplantation [PDF]
arXiv, 2019 One of the biggest challenges in medicine is to dampen the pathophysiological stress induced by an episode of ischemia. Such stress, due to various pathological or clinical situations, follows a restriction in blood and oxygen supply to tissue, causing a shortage of oxygen and nutrients that are required for cellular metabolism.
arxiv
Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease
Aggregate, EarlyView.This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang +4 more
wiley +1 more source
Cancer, Volume 129, Issue 3, Page 426-440, 1 February 2023., 2023 Abstract Background Survivors of Hodgkin lymphoma (HL) are at risk of developing non‐Hodgkin lymphoma (NHL) after treatment; however, the risks of developing subsequent primary lymphomas (SPLs), including HL and NHL, after different types of childhood cancer are unknown.
Isabelle M. Dudley +38 more
wiley +1 more source
Classification with Ultrahigh-Dimensional Features [PDF]
arXiv, 2016 Although much progress has been made in classification with high-dimensional features \citep{Fan_Fan:2008, JGuo:2010, CaiSun:2014, PRXu:2014}, classification with ultrahigh-dimensional features, wherein the features much outnumber the sample size, defies most existing work.
arxiv
Changes in leucocyte migration after renal transplantation [PDF]
, 1969 M. G. M. Smith +5 more
openalex +1 more source
Vascular co‐option and vasculogenic mimicry mediate resistance to antiangiogenic strategies
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The concept that all the tumors need the formation of new vessels to grow inspired the hypothesis that inhibition of angiogenesis would have led to “cure” cancer. The expectancy that this type of therapy would have avoided the insurgence of resistance was based on the concept that targeting normal vessels, instead of the cancer ...
Francesco Pezzella, Domenico Ribatti
wiley +1 more source
TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management
American Journal of Hematology, EarlyView.ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah +2 more
wiley +1 more source