Results 121 to 130 of about 190,539 (312)

Radiosensitization of calreticulin‐overexpressing human glioma cell line by the polyphenolic acetate 7, 8‐diacetoxy‐4‐methylcoumarin

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma   +6 more
wiley   +1 more source

Choroidal image analysis for OCT image sequences with applications in systemic health [PDF]

open access: yes
The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with blood flow far exceeding that of the brain and kidney. Thus, there has been growing interest of choroidal blood flow reflecting physiological status of systemic disease.
arxiv   +1 more source

Survival after renal transplantation in man: an interim report on 54 consecutive transplants. [PDF]

open access: bronze, 1968
R. Y. Calne   +10 more
openalex   +1 more source

Phenotypical Characterization of Gastroenterological and Metabolic Manifestations in Patients With Williams–Beuren Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gastrointestinal (GI) symptoms are common in patients with Williams–Beuren syndrome (WBS), but their prevalence and possible causes are not yet fully known. This study assessed GI symptoms' prevalence and their possible origin by performing a predefined set of tests in adult WBS patients.
Maria Francesca Bedeschi   +10 more
wiley   +1 more source

Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis

open access: yesCancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade   +2 more
wiley   +1 more source

Sequential Pattern mining of Longitudinal Adverse Events After Left Ventricular Assist Device Implant [PDF]

open access: yesarXiv, 2019
Left ventricular assist devices (LVADs) are an increasingly common therapy for patients with advanced heart failure. However, implantation of the LVAD increases the risk of stroke, infection, bleeding, and other serious adverse events (AEs). Most post-LVAD AEs studies have focused on individual AEs in isolation, neglecting the possible interrelation ...
arxiv  

The utility of split function testing in determining recovery of glomerular filtration rate after living kidney donation: a cohort study

open access: yesBMC Nephrology
Background A number of UK transplantation centres use isotope studies to estimate the relative contribution from each kidney in living kidney donor assessment.
Kirsty J. Crowe   +6 more
doaj   +1 more source

Application of humanized mice in the safety experiments of antibody drugs

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun   +9 more
wiley   +1 more source

Type 1 diabetes recurrence after SARS‐CoV‐2 infection in a subject with pancreas transplantation

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV2 infection and diabetes mellitus. Little is known about the effects of SARS‐CoV‐2 infection on glycaemic control in pancreas transplant patients. Abstract Background During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV‐2 ...
Valentina Popolla   +4 more
wiley   +1 more source

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