Advanced Science, EarlyView.Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang +14 more
wiley +1 more source
Safety of sofosbuvir‐based regimens after liver transplantation: longitudinal assessment of renal function in the prospective
, 2018 Rodolphe Anty +38 more
openalex +1 more source
Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks
Advanced Science, EarlyView.This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen +11 more
wiley +1 more source
008 Post renal transplant CMV infection – A single centre experience
, 2010 Kute Vivek +12 more
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Effect of hematocrit on cyclosporine (cyclosporin A) in whole blood and plasma of renal-transplant patients. [PDF]
, 1985 T G Rosano
openalex +1 more source
P1626LIQUID BIOPSY IN RENAL TRANSPLANT: THE ROLE OF DONOR-DERIVED CELL-FREE DNA TO DETECT REJECTION [PDF]
, 2020 Mattia Rossi +2 more
openalex +1 more source
Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex
Advanced Science, EarlyView.In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang +13 more
wiley +1 more source
A case of sickle-cell erythrocytosis occurring following renal transplantation [PDF]
, 2002 B. Myers, S. M. Donohue
openalex +1 more source
Droplet Digital CRISPR for Nucleic Acid Detection
Advanced Science, EarlyView.This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang +4 more
wiley +1 more source
Effect of losartan on haemoglobin concentration in renal transplant recipients - a retrospective analysis [PDF]
, 1997 Ludivine Dal Zuffo +2 more
openalex +1 more source