Results 191 to 200 of about 191,659 (311)

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

BKPyV-Co-Architect of the Fate of a Renal Transplant During a One-Year Observation Period. [PDF]

open access: yesInt J Mol Sci
Furmaga J   +10 more
europepmc   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

WCN25-2244 DIARRHEA IN RENAL TRANSPLANT RECIPIENTS: AN OBSERVATIONAL CROSS-SECTIONAL STUDY IN NORTH INDIA

open access: yesKidney International Reports
Dinesh Khullar   +7 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli   +6 more
wiley   +1 more source

WCN25-2556 OCCUPATIONAL HEALTH RISKS AND RENAL DYSFUNCTION IN NORTH INDIAN AUTO-RICKSHAW DRIVERS

open access: yesKidney International Reports
ANISH GUPTA   +8 more
doaj   +1 more source

Anti-PD-1-induced bullous pemphigoid in a renal transplant recipient. [PDF]

open access: yesSAGE Open Med Case Rep
Barnawi G   +5 more
europepmc   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

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